Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 2/20 | 0.53 |
| ▸ | MASP2 | O00187 | 1/20 | 0.53 |
| ▸ | THPO | P40225 | 1/20 | 0.53 |
| ▸ | F2 | P00734 | 6/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.52 |
| ▸ | PRSS3 | P35030 | 5/20 | 0.52 |
| ▸ | APEX1 | P27695 | 1/20 | 0.52 |
| ▸ | F10 | P00742 | 2/20 | 0.46 |
| ▸ | F12 | P00748 | 1/20 | 0.46 |
| ▸ | F7 | P08709 | 1/20 | 0.46 |
| ▸ | F3 | P13726 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.45 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | WDR5 | P61964 | 1/20 | 0.44 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | C1S | P09871 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenylmethanesulfonic Acid SCHEMBL7148383 | 0.94 | F2 (0.52) | PLAUF2PRSS1PRSS3F10 | |
| SCHEMBL11547040 | 0.85 | F10 (0.61) | PLAUMASP2THPOF2PRSS1 | |
| Ammonia Solution, Strong SCHEMBL11392652 | 0.83 | F10 (0.59) | PLAUMASP2THPOF2PRSS1 | |
| Phenylmethanesulfonic Acid SCHEMBL9752378 | 0.83 | CA1 (0.54) | F2PRSS1PRSS3PRSS2LOXL2 | |
| Hydrochloric Acid SCHEMBL11396972 | 0.82 | F10 (0.57) | THPOF2PRSS1PRSS3APEX1 | |
| SCHEMBL8170318 | 0.78 | TSHR (0.68) | PLAUF2PRSS1PRSS3F10 | |
| SCHEMBL1335821 | 0.77 | TSHR (0.50) | LOXL2RECQLCA1CA2CA5A | |
| Phenylmethanesulfonic Acid SCHEMBL1749 | 0.77 | CA2 (0.58) | F2PRSS1PRSS3PRSS2BLM | |
| Phenylmethanesulfonic Acid SCHEMBL127384 | 0.77 | CA2 (0.58) | F2PRSS1PRSS3PRSS2BLM | |
| Phenylmethanesulfonic Acid SCHEMBL30217949 | 0.77 | CA2 (0.58) | F2PRSS1PRSS3PRSS2BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0921116-B1 | N-(4-carbamimido-phenyl)-glycine amide derivatives | HOFFMANN LA ROCHE (CH) | 2003-06-18 | — | — | EP | disclosed |
| EP-0921116-A1 | N-(4-carbamimido-phenyl)-glycine amide derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1999-06-09 | — | — | EP | disclosed |