Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.32 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.32 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.32 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.32 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | TACR2 | P21452 | 1/20 | 0.32 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7144856 | 0.99 | CYP3A4 (0.32) | CYP3A4ABCC3ABCC4CACNA1FABCB11 | |
| SCHEMBL7356317 | 0.87 | F2 (0.37) | LMNAUSP2MEN1ACEKMT2A | |
| Hydrochloric Acid SCHEMBL7165069 | 0.86 | F2 (0.37) | LMNAUSP2MEN1ACEKMT2A | |
| SCHEMBL7139402 | 0.84 | PTGER4 (0.36) | LMNAUSP2MEN1ACEKMT2A | |
| SCHEMBL7143011 | 0.82 | F2 (0.35) | CYP3A4LMNAUSP2MEN1ACE | |
| SCHEMBL7148085 | 0.81 | CTSD (0.33) | MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7364149 | 0.81 | F2 (0.34) | LMNAUSP2MEN1ACEKMT2A | |
| Hydrochloric Acid SCHEMBL7146333 | 0.81 | CTSD (0.32) | MEN1KMT2A | |
| SCHEMBL7249203 | 0.80 | MC3R (0.33) | CYP3A4ABCC3ABCC4CACNA1FABCB11 | |
| Hydrochloric Acid SCHEMBL7160547 | 0.80 | MC3R (0.33) | CYP3A4ABCC3ABCC4CACNA1FABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1361212-A1 | Peptide derivatives as antithrombotic agents | AstraZeneca AB (SE) | 2003-11-12 | — | — | EP | claimed |
| EP-0672658-A1 | Antithrombotic agents | ELI LILLY AND COMPANY (US) | 1995-09-20 | — | — | EP | claimed |
| WO-1995023609-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1995-09-08 | — | — | WO | claimed |