Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.70 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.70 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.70 |
| ▸ | NR1I2 | O75469 | 5/20 | 0.53 |
| ▸ | HTR2C | P28335 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | FAP | Q12884 | 1/20 | 0.52 |
| ▸ | ALB | P02768 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.52 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.52 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.52 |
| ▸ | PGR | P06401 | 2/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.51 |
| ▸ | APEX1 | P27695 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7148779 | 1.00 | PTGS1 (0.70) | PTGS1ABCB11PDE4DNR1I2HTR2C | |
| SCHEMBL5099296 | 1.00 | PTGS1 (0.70) | PTGS1ABCB11PDE4DNR1I2HTR2C | |
| SCHEMBL7148776 | 0.88 | NR1I2 (0.66) | PTGS1NR1I2HTR2CMAPTALDH1A1 | |
| SCHEMBL5098930 | 0.88 | NR1I2 (0.66) | PTGS1NR1I2HTR2CMAPTALDH1A1 | |
| SCHEMBL9434513 | 0.84 | PTGS1 (0.72) | PTGS1ABCB11PDE4DNR1I2HTR2C | |
| Cefpodoxime Proxetil SCHEMBL6136644 | 0.83 | PTGS1 (1.00) | PTGS1ABCB11PDE4DNR1I2HTR2C | |
| Cefpodoxime Proxetil SCHEMBL614583 | 0.83 | PTGS1 (1.00) | PTGS1ABCB11PDE4DNR1I2HTR2C | |
| Cefpodoxime Proxetil SCHEMBL379709 | 0.83 | PTGS1 (1.00) | PTGS1ABCB11PDE4DNR1I2HTR2C | |
| Cefpodoxime Proxetil SCHEMBL22330291 | 0.83 | PTGS1 (1.00) | PTGS1ABCB11PDE4DNR1I2HTR2C | |
| Cefpodoxime Proxetil SCHEMBL27071 | 0.83 | PTGS1 (1.00) | PTGS1ABCB11PDE4DNR1I2HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7317101-B2 | Antibacterial cephalosporins | SANDOZ GMBH (AT) | 2008-01-08 | — | — | US | disclosed |
| US-20030191105-A1 | Antibacterial cephalosporins | NABRIVA THERAPEUTICS AG (AT) | 2003-10-09 | — | — | US | disclosed |
| EP-0824535-B1 | ANTIBACTERIAL CEPHALOSPORINS | BIOCHEMIE GMBH (AT) | 2003-02-26 | — | — | EP | disclosed |
| EP-1221446-A1 | Antibacterial cephalosporins | BIOCHEMIE Gesellschaft m.b.H. (AT) | 2002-07-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030191105-A1 | Antibacterial cephalosporins | MRPL21, CIAPIN1, CSDE1 | PTGS1 628/4885ABCB11 127/4885PDE4D 2018/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.