Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.70 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.70 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.70 |
| ▸ | NR1I2 | O75469 | 5/20 | 0.53 |
| ▸ | HTR2C | P28335 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | FAP | Q12884 | 1/20 | 0.52 |
| ▸ | ALB | P02768 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.52 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.52 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.52 |
| ▸ | PGR | P06401 | 2/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.51 |
| ▸ | APEX1 | P27695 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5099292 | 1.00 | PTGS1 (0.70) | PTGS1ABCB11PDE4DNR1I2HTR2C | |
| SCHEMBL5099296 | 1.00 | PTGS1 (0.70) | PTGS1ABCB11PDE4DNR1I2HTR2C | |
| SCHEMBL7148776 | 0.88 | NR1I2 (0.66) | PTGS1NR1I2HTR2CMAPTALDH1A1 | |
| SCHEMBL5098930 | 0.88 | NR1I2 (0.66) | PTGS1NR1I2HTR2CMAPTALDH1A1 | |
| SCHEMBL9434513 | 0.84 | PTGS1 (0.72) | PTGS1ABCB11PDE4DNR1I2HTR2C | |
| Cefpodoxime Proxetil SCHEMBL6136644 | 0.83 | PTGS1 (1.00) | PTGS1ABCB11PDE4DNR1I2HTR2C | |
| Cefpodoxime Proxetil SCHEMBL614583 | 0.83 | PTGS1 (1.00) | PTGS1ABCB11PDE4DNR1I2HTR2C | |
| Cefpodoxime Proxetil SCHEMBL379709 | 0.83 | PTGS1 (1.00) | PTGS1ABCB11PDE4DNR1I2HTR2C | |
| Cefpodoxime Proxetil SCHEMBL22330291 | 0.83 | PTGS1 (1.00) | PTGS1ABCB11PDE4DNR1I2HTR2C | |
| Cefpodoxime Proxetil SCHEMBL27071 | 0.83 | PTGS1 (1.00) | PTGS1ABCB11PDE4DNR1I2HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6531465-B1 | 7-acylamino-3-(imino)methyl cephalosporins; 7-[[(5-Amino-1,2,4-thiadiazol-3-yl)-(Z)-(fluormethoxyimino)acetyl]amino]-3-[[(piperazinoiminomethyl)hydrazono]methyl]-3-cephem-4-carboxylic acid; imination of 3-methyl derivative; acylation at the 7-amino; 1-[hydrazino(methylimino)methyl]piperazine intermediate | BIOCHEMIE GESELLSCHAFT M.B.H. (AT) | 2003-03-11 | — | — | US | disclosed |