SCHEMBL7149277

SCHEMBL7149277

O=C(C(F)(F)F)C(F)(F)F.[N]

nearest known ligand 0.39

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.39
CES2 O00748 1/20 0.36
ALDH1A1 P00352 1/20 0.32
POLB P06746 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
CES1 P23141 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL344 0.95 CA2 (0.41) CA2CES2ALDH1A1POLBSMN1; SMN2
SCHEMBL27892503 0.95 CA2 (0.41) CA2CES2ALDH1A1POLBSMN1; SMN2
Hydrogen Peroxide SCHEMBL6668489 0.91 CA2 (0.39) CA2CES2ALDH1A1POLBSMN1; SMN2
Water SCHEMBL581158 0.91 CA2 (0.39) CA2CES2ALDH1A1POLBSMN1; SMN2
Hydrochloric Acid SCHEMBL7628909 0.91 CA2 (0.39) CA2CES2ALDH1A1POLBSMN1; SMN2
Fluoride SCHEMBL1594462 0.91 CA2 (0.39) CA2CES2ALDH1A1POLBSMN1; SMN2
SCHEMBL11799381 0.91 CA2 (0.39) CA2CES2ALDH1A1POLBSMN1; SMN2
SCHEMBL9473581 0.91 CA2 (0.39) CA2CES2ALDH1A1POLBSMN1; SMN2
SCHEMBL15540711 0.91 CA2 (0.39) CA2CES2ALDH1A1POLBSMN1; SMN2
SCHEMBL11421274 0.91 CA2 (0.39) CA2CES2ALDH1A1POLBSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003059991-A1 CHEMOSELECTIVE DENDRIMERIC COMPOUNDS FOR USE IN CHEMICAL SENSORS THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2003-07-24 WO disclosed