Fluoride

Fluoride

SCHEMBL1594462

F.O=C(C(F)(F)F)C(F)(F)F

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.39
CES2 O00748 1/20 0.36
ALDH1A1 P00352 1/20 0.32
POLB P06746 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
CES1 P23141 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoride SCHEMBL28787348 0.96 CA2 (0.37) CA2CES2ALDH1A1POLBSMN1; SMN2
SCHEMBL344 0.95 CA2 (0.41) CA2CES2ALDH1A1POLBSMN1; SMN2
SCHEMBL27892503 0.95 CA2 (0.41) CA2CES2ALDH1A1POLBSMN1; SMN2
Water SCHEMBL18544564 0.91 CA2 (0.39) CA2CES2ALDH1A1POLBSMN1; SMN2
Water SCHEMBL581158 0.91 CA2 (0.39) CA2CES2ALDH1A1POLBSMN1; SMN2
SCHEMBL11800353 0.91 CA2 (0.39) CA2CES2ALDH1A1POLBSMN1; SMN2
SCHEMBL11421274 0.91 CA2 (0.39) CA2CES2ALDH1A1POLBSMN1; SMN2
SCHEMBL9473581 0.91 CA2 (0.39) CA2CES2ALDH1A1POLBSMN1; SMN2
Hydrogen Peroxide SCHEMBL6668489 0.91 CA2 (0.39) CA2CES2ALDH1A1POLBSMN1; SMN2
SCHEMBL15540711 0.91 CA2 (0.39) CA2CES2ALDH1A1POLBSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2189437-B1 ROCESS FOR DEHYDRATION OF HEXAFLUOROACETONE TRIHYDRATE CENTRAL GLASS CO LTD (JP) 2016-10-12 EP claimed
CN-101784510-B Dehydration method of hexafluoroacetone hydrate CENTRAL GLASS CO LTD 2013-03-20 CN claimed
US-7919657-B2 Process for dehydration of hexafluoroacetone hydrate CENTRAL GLASS COMPANY, LIMITED (JP) 2011-04-05 US claimed
US-20100217049-A1 Process for Dehydration of Hexafluoroacetone Hydrate CENTRAL GLASS COMPANY, LIMITED (JP) 2010-08-26 US claimed
CN-101784510-A Dehydration method of hexafluoroacetone hydrate CENTRAL GLASS CO LTD 2010-07-21 CN claimed
EP-2189437-A1 PROCESS FOR DEHYDRATION OF HEXAFLUOROACETONE HYDRATE Central Glass Company, Limited (JP) 2010-05-26 EP claimed
CN-122010698-A Preparation method of perfluoromethoxy methylene vinyl ether 漳平市九鼎泰天科技有限公司 2026-05-12 CN disclosed
CN-114591158-B Method and device for preparing pentafluoropropionyl fluoride and hexafluoroacetone from perfluoro-2-methyl-2-pentene 福建省漳平市九鼎氟化工有限公司 2024-01-30 CN disclosed
CN-114591158-A Method and device for preparing pentafluoropropionyl fluoride and hexafluoroacetone from perfluoro-2-methyl-2-pentene 福建省漳平市九鼎氟化工有限公司 2022-06-07 CN disclosed
EP-3364486-A1 NONAQUEOUS ELECTROLYTE SECONDARY BATTERY GS Yuasa International Ltd. (JP) 2018-08-22 EP disclosed
EP-2189437-B1 ROCESS FOR DEHYDRATION OF HEXAFLUOROACETONE TRIHYDRATE CENTRAL GLASS CO LTD (JP) 2016-10-12 EP disclosed
EP-2189437-A4 PROCESS FOR DEHYDRATION OF HEXAFLUOROACETONE HYDRATE CENTRAL GLASS CO LTD (JP) 2013-11-20 EP disclosed
CN-101784510-B Dehydration method of hexafluoroacetone hydrate CENTRAL GLASS CO LTD 2013-03-20 CN disclosed
JP-2009051799-A DEHYDRATION METHOD OF HEXAFLUOROACETONE HYDRATE CENTRAL GLASS CO LTD 2009-03-12 JP disclosed
EP-0232329-B1 PERFLUORINATED POLYETHER FLUIDS Lagow, Richard J. (US) 1990-10-03 EP disclosed
EP-0232329-A1 PERFLUORINATED POLYETHER FLUIDS. LAGOW RICHARD J (US) 1987-08-19 EP disclosed
US-4675452-A LUBRICANTS LAGOW RICHARD J (US) 1987-06-23 US disclosed
WO-1987000538-A1 PERFLUORINATED POLYETHER FLUIDS LAGOW RICHARD J 1987-01-29 WO disclosed
US-4059633-A Recovery of hexafluoroacetone from a hexafluoroacetone-HF control PHILLIPS PETROLEUM COMPANY (US) 1977-11-22 US disclosed
US-3745093-A PROCESS FOR SEPARATING HEXAFLUOROACETONE FROM HYDROGEN FLUORIDE DU PONT 1973-07-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100217049-A1 Process for Dehydration of Hexafluoroacetone Hydrate PFAS, HDHD5, PFKFB1 CA2 217/4885CES2 3964/4885ALDH1A1 865/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.