Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Isosorbide Dinitrate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.95 |
| ▸ | MAPT | P10636 | 1/20 | 0.75 |
| ▸ | BCHE | P06276 | 6/20 | 0.62 |
| ▸ | GSR | P00390 | 8/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isosorbide Dinitrate SCHEMBL9439417 | 0.98 | ALDH1A1 (1.00) | ALDH1A1MAPTBCHEGSRCA2 | |
| Isosorbide Dinitrate SCHEMBL1553054 | 0.98 | ALDH1A1 (1.00) | ALDH1A1MAPTBCHEGSRCA2 | |
| Isosorbide Dinitrate SCHEMBL29532755 | 0.98 | ALDH1A1 (1.00) | ALDH1A1MAPTBCHEGSRCA2 | |
| Isosorbide Dinitrate SCHEMBL309369 | 0.98 | ALDH1A1 (1.00) | ALDH1A1MAPTBCHEGSRCA2 | |
| Isosorbide Dinitrate SCHEMBL8253 | 0.98 | ALDH1A1 (1.00) | ALDH1A1MAPTBCHEGSRCA2 | |
| Isosorbide Dinitrate SCHEMBL19528695 | 0.98 | ALDH1A1 (1.00) | ALDH1A1MAPTBCHEGSRCA2 | |
| Isosorbide Dinitrate SCHEMBL3008938 | 0.95 | ALDH1A1 (0.95) | ALDH1A1MAPTBCHEGSRCA2 | |
| Isosorbide Dinitrate SCHEMBL28209664 | 0.93 | ALDH1A1 (0.91) | ALDH1A1MAPTBCHEGSRCA2 | |
| Isosorbide Dinitrate SCHEMBL27976716 | 0.93 | ALDH1A1 (0.91) | ALDH1A1MAPTBCHEGSRCA2 | |
| Isosorbide Dinitrate SCHEMBL3864281 | 0.91 | ALDH1A1 (0.88) | ALDH1A1MAPTBCHEGSRCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102399466-A | Ink jet ink composition, ink jet recording method, ink cartridge, recording unit, and ink jet recording apparatus | SONY CORP | 2012-04-04 | — | — | CN | disclosed |
| CN-102382500-A | Ink jet ink composition, ink jet recording method, ink cartridge, recording unit, and ink jet recording apparatus | SONY CORP | 2012-03-21 | — | — | CN | disclosed |
| US-20120050382-A1 | INK JET INK COMPOSITION, INK JET RECORDING METHOD, INK CARTRIDGE, RECORDING UNIT, AND INK JET RECORDING APPARATUS | SONY CORPORATION (JP) | 2012-03-01 | — | — | US | disclosed |
| US-20120050381-A1 | INK JET INK COMPOSITION, INK JET RECORDING METHOD, INK CARTRIDGE, RECORDING UNIT, AND INK JET RECORDING APPARATUS | SONY CORPORATION (JP) | 2012-03-01 | — | — | US | disclosed |
| US-5161549-A | Retaining tar, nicotine and noxious gases in tobacco smoke filter by mixing in aqueous medium two organic acids, two organic acid salts, organic acid and salt, two polyhydric alcohols, or salt of organic acid and polyhydric alcohol | REGIONAL RESEARCH & DEVELOPMENT CORPORATION (US) | 1992-11-10 | — | — | US | disclosed |
| WO-1991014381-A1 | PURE CLEAN CIGARETTE FILTER | REGIONAL RESEARCH & DEVELOPMENT CORPORATION (US) | 1991-10-03 | — | — | WO | disclosed |