SCHEMBL7149973

SCHEMBL7149973

Cc1ccc(S(=O)(=O)NN)cc1.NNS(=O)(=O)c1ccc(Oc2ccc(S(=O)(=O)NN)cc2)cc1

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.59
ALDH1A1 P00352 5/20 0.59
SMN1; SMN2 Q16637 4/20 0.59
HTT P42858 4/20 0.58
LMNA P02545 1/20 0.58
GFER P55789 1/20 0.54
GAA P10253 1/20 0.52
TDP1 Q9NUW8 2/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
MMP1 P03956 1/20 0.50
MMP2 P08253 1/20 0.50
MMP9 P14780 1/20 0.50
MMP8 P22894 1/20 0.50
MMP13 P45452 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
TEAD4 Q15561 1/20 0.48
CYP2C9 P11712 2/20 0.48
CYP1A2 P05177 1/20 0.48
CYP2C19 P33261 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL36774 0.90 SMN1; SMN2 (0.63) FFAR1ALDH1A1SMN1; SMN2HTTLMNA
SCHEMBL250755 0.88 GAA (0.64) ALDH1A1SMN1; SMN2LMNAGFERGAA
SCHEMBL9091 0.88 GAA (0.64) ALDH1A1SMN1; SMN2LMNAGFERGAA
SCHEMBL28554322 0.86 SMN1; SMN2 (0.61) ALDH1A1SMN1; SMN2LMNAGAATDP1
Hydrochloric Acid SCHEMBL4639536 0.86 SMN1; SMN2 (0.61) ALDH1A1SMN1; SMN2LMNAGAATDP1
Water SCHEMBL27947230 0.86 SMN1; SMN2 (0.61) ALDH1A1SMN1; SMN2LMNAGAATDP1
SCHEMBL6681003 0.83 SOS1 (0.63) FFAR1ALDH1A1SMN1; SMN2HTTLMNA
SCHEMBL8736878 0.83 SMN1; SMN2 (0.85) FFAR1ALDH1A1SMN1; SMN2HTTLMNA
SCHEMBL11844270 0.81 ALDH1A1 (0.54) ALDH1A1SMN1; SMN2HTTLMNACA1
SCHEMBL3402420 0.81 ALDH1A1 (0.51) FFAR1ALDH1A1SMN1; SMN2HTTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030087085-A1 Polymer composition for powder molding, powder thereof, foamed articles, and method for producing foamed article SUMITOMO CHEMICAL COMPANY, LIMITED 2003-05-08 US disclosed
US-6534167-B1 Polymer composition for power molding, power thereof, foamed object, and process for producing foamed object SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-03-18 US disclosed