Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 1/20 | 0.63 |
| ▸ | PGR | P06401 | 4/20 | 0.61 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.57 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.54 |
| ▸ | MMP1 | P03956 | 1/20 | 0.54 |
| ▸ | MMP2 | P08253 | 1/20 | 0.54 |
| ▸ | MMP13 | P45452 | 1/20 | 0.54 |
| ▸ | MMP14 | P50281 | 1/20 | 0.54 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.54 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 2/20 | 0.53 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL36774 | 0.92 | SMN1; SMN2 (0.63) | SOS1PGRFFAR1FFAR4SMN1; SMN2 | |
| Diphenylether SCHEMBL11224503 | 0.91 | MAOA (0.57) | SOS1PGRFFAR1FFAR4SMN1; SMN2 | |
| SCHEMBL11844270 | 0.83 | ALDH1A1 (0.54) | SOS1PGRSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL7149973 | 0.83 | FFAR1 (0.59) | FFAR1SMN1; SMN2ALDH1A1LMNAHTT | |
| SCHEMBL18261208 | 0.81 | SMN1; SMN2 (0.49) | SOS1PGRSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL11400434 | 0.81 | SMN1; SMN2 (0.49) | SOS1PGRFFAR1FFAR4SMN1; SMN2 | |
| SCHEMBL1109 | 0.81 | CA1 (0.58) | SMN1; SMN2ALDH1A1LMNAKDM4EMMP1 | |
| SCHEMBL30724544 | 0.81 | CA1 (0.58) | SMN1; SMN2ALDH1A1LMNAKDM4EMMP1 | |
| SCHEMBL618590 | 0.81 | LMNA (0.85) | SOS1PGRFFAR1FFAR4SMN1; SMN2 | |
| SCHEMBL10768121 | 0.80 | PGR (0.65) | SOS1PGRFFAR1FFAR4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004058238-A1 | USE OF CATHEPSIN K INHIBITORS FOR THE TREATMENT OF GLAUCOMA | ALCON, INC. (CH) | 2004-07-15 | — | — | WO | claimed |
| WO-2004058238-A1 | USE OF CATHEPSIN K INHIBITORS FOR THE TREATMENT OF GLAUCOMA | ALCON, INC. (CH) | 2004-07-15 | — | — | WO | disclosed |