Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 1/20 | 0.43 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.43 |
| ▸ | FDPS | P14324 | 13/20 | 0.40 |
| ▸ | PGK1 | P00558 | 2/20 | 0.39 |
| ▸ | PGK2 | P07205 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15163959 | 0.77 | PGK1 (0.46) | LPAR1LPAR3FDPSPGK1PGK2 | |
| SCHEMBL1533912 | 0.77 | — | — | |
| SCHEMBL1831474 | 0.75 | PTPN1 (0.43) | FDPS | |
| SCHEMBL26323421 | 0.74 | — | — | |
| SCHEMBL776697 | 0.72 | LPAR1 (0.40) | LPAR1LPAR3FDPSPGK1PGK2 | |
| SCHEMBL17476332 | 0.71 | LPAR1 (0.70) | LPAR1LPAR3FDPSGGPS1 | |
| SCHEMBL21101672 | 0.69 | LPAR1 (0.68) | LPAR1LPAR3FDPSGGPS1 | |
| SCHEMBL1768259 | 0.69 | FDPS (0.43) | LPAR1LPAR3FDPSLMNAGGPS1 | |
| SCHEMBL246809 | 0.69 | FDPS (0.43) | LPAR1LPAR3FDPSLMNAGGPS1 | |
| SCHEMBL6296955 | 0.69 | FDPS (0.43) | LPAR1LPAR3FDPSLMNAGGPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6531459-B1 | Therapy of or prophylaxis against osteoporosis; generating new bone material; treating disease characterized by hyperproliferation and deficient cell differentiation | SCHERING AKTIENGESELLSCHAFT (DE) | 2003-03-11 | — | — | US | disclosed |
| EP-1042335-A1 | VITAMIN D DERIVATIVES WITH PHOSPHOROUS ATOMS IN THE SIDE CHAINS | SCHERING AKTIENGESELLSCHAFT (DE) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999031112-A1 | VITAMIN D DERIVATIVES WITH PHOSPHOROUS ATOMS IN THE SIDE CHAINS | SCHERING AKTIENGESELLSCHAFT (DE) | 1999-06-24 | — | — | WO | disclosed |
| CN-1031713-C | 9-purinyl phosphonic acid derivatives | MERRELL PHARMA INC (US) | 1996-05-01 | — | — | CN | disclosed |
| CN-1058021-A | The 9-purinyl phosphonic acid derivatives | MERRELL DOW PHARMA (US) | 1992-01-22 | — | — | CN | disclosed |
| EP-0331550-A1 | Novel aspartate transcarbamylase inhibitors | MERRELL DOW PHARMACEUTICALS INC. (US) | 1989-09-06 | — | — | EP | disclosed |
| EP-0328834-A1 | Novel aspartate transcarbamylase inhibitors | MERRELL DOW PHARMACEUTICALS INC. (US) | 1989-08-23 | — | — | EP | disclosed |