Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 7/20 | 0.53 |
| ▸ | F3 | P13726 | 3/20 | 0.53 |
| ▸ | F2 | P00734 | 7/20 | 0.52 |
| ▸ | F10 | P00742 | 6/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | F11 | P03951 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7150576 | 1.00 | F7 (0.53) | F7F3F2F10PRSS1 | |
| SCHEMBL7144712 | 0.89 | F7 (0.65) | F7F3F2F10PRSS1 | |
| SCHEMBL7144720 | 0.89 | F7 (0.65) | F7F3F2F10PRSS1 | |
| Acetic Acid SCHEMBL8114249 | 0.89 | F7 (0.64) | F7F3F2F10PRSS1 | |
| SCHEMBL5883990 | 0.85 | ALDH1A1 (0.43) | F7F3F2F10PRSS1 | |
| SCHEMBL7149677 | 0.82 | F7 (0.54) | F7F3F2F10PRSS1 | |
| SCHEMBL7149660 | 0.82 | F7 (0.54) | F7F3F2F10PRSS1 | |
| SCHEMBL7148395 | 0.80 | F7 (0.56) | F7F3F2F10PRSS1 | |
| SCHEMBL7148405 | 0.80 | F7 (0.56) | F7F3F2F10PRSS1 | |
| SCHEMBL7148384 | 0.80 | F7 (0.56) | F7F3F2F10PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0921116-B1 | N-(4-carbamimido-phenyl)-glycine amide derivatives | HOFFMANN LA ROCHE (CH) | 2003-06-18 | — | — | EP | disclosed |
| US-6140353-A | USED AS MEDICAMENTS FOR THE TREATMENT AND/OR PREVENTION OF THROMBOSES, APOPLEXY, CARDIAC INFARCTION, INFLAMMATION AND ARTERIOSCLEROSIS OR AS ANTITUMOR AGENTS | HOFFMANN-LA ROCHE INC. (US) | 2000-10-31 | — | — | US | disclosed |
| EP-0921116-A1 | N-(4-carbamimido-phenyl)-glycine amide derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1999-06-09 | — | — | EP | disclosed |