Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 9/20 | 0.46 |
| ▸ | NPY1R | P25929 | 9/20 | 0.37 |
| ▸ | ACP1 | P24666 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7152745 | 0.94 | LSS (0.47) | LSSNPY1R | |
| SCHEMBL7145197 | 0.90 | LSS (0.57) | LSS | |
| SCHEMBL7152838 | 0.87 | LSS (0.55) | LSS | |
| SCHEMBL7149010 | 0.84 | LSS (0.59) | LSS | |
| SCHEMBL7149946 | 0.83 | LSS (0.46) | LSS | |
| SCHEMBL7145283 | 0.82 | LSS (0.54) | LSSACP1 | |
| SCHEMBL7152044 | 0.79 | LSS (0.59) | LSS | |
| SCHEMBL5040185 | 0.78 | LSS (0.57) | LSS | |
| SCHEMBL5035555 | 0.77 | LSS (0.58) | LSS | |
| SCHEMBL7144752 | 0.76 | LSS (0.63) | LSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1334094-A1 | CHOLESTEROL LOWERING BENZO[B]THIOPHENES AND BENZO[D]ISOTHIAZOLES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-08-13 | — | — | EP | disclosed |
| WO-2002036584-A1 | CHOLESTEROL LOWERING BENZO`B! THIOPHENES AND BENZO`D! ISOTHIAZOLES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-05-10 | — | — | WO | disclosed |