Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL7152732

CS(=O)(=O)Nc1ccc(Oc2ccc(C(=N)N)cc2)c(C(=O)O)c1.O=C(O)C(F)(F)F

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
F10 P00742 3/20 0.47
BRD4 O60885 1/20 0.45
SLC6A2 P23975 1/20 0.44
SLC6A4 P31645 1/20 0.44
SLC6A3 Q01959 1/20 0.44
F3 P13726 8/20 0.44
F2 P00734 8/20 0.44
F7 P08709 1/20 0.43
MRGPRX1 Q96LB2 6/20 0.43
PRSS1 P07477 1/20 0.41
PRSS2 P07478 1/20 0.41
PRSS3 P35030 1/20 0.41
ST14 Q9Y5Y6 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL7154799 0.97 F10 (0.49) F10BRD4SLC6A2SLC6A4SLC6A3
Trifluoroacetic Acid SCHEMBL6300672 0.92 F10 (0.48) F10F3F2F7
Trifluoroacetic Acid SCHEMBL7153335 0.88 BRD4 (0.51) F10BRD4SLC6A2SLC6A4SLC6A3
Trifluoroacetic Acid SCHEMBL7151889 0.87 F2 (0.51) F3F2MRGPRX1PRSS1PRSS2
SCHEMBL7152737 0.86 F10 (0.46) F10BRD4SLC6A2SLC6A4SLC6A3
Trifluoroacetic Acid SCHEMBL7151221 0.85 ST14 (0.62) F10F2MRGPRX1PRSS1PRSS2
SCHEMBL8506821 0.85 F10 (0.52) F10BRD4F3F2F7
Trifluoroacetic Acid SCHEMBL7154599 0.84 F10 (0.43) F10F3F2F7PRSS1
Trifluoroacetic Acid SCHEMBL7158334 0.83 BRD4 (0.46) F10BRD4F3F2MRGPRX1
Trifluoroacetic Acid SCHEMBL7156674 0.83 PRSS1 (0.61) F10F3F2F7MRGPRX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1312602-A1 Amidino derivatives, and anticoagulants and thrombosis therapeutic agents containing them Eisai Co., Ltd. (JP) 2003-05-21 EP disclosed