Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 9/20 | 0.79 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.65 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.60 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.59 |
| ▸ | FAAH | O00519 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.53 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.53 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL872599 | 1.00 | NOD1 (0.79) | NOD1PLA2G2CPLA2G10SLC6A5FAAH | |
| SCHEMBL8728931 | 1.00 | NOD1 (0.79) | NOD1PLA2G2CPLA2G10SLC6A5FAAH | |
| SCHEMBL7942033 | 1.00 | NOD1 (0.79) | NOD1PLA2G2CPLA2G10SLC6A5FAAH | |
| SCHEMBL536128 | 1.00 | NOD1 (0.79) | NOD1PLA2G2CPLA2G10SLC6A5FAAH | |
| SCHEMBL714530 | 1.00 | NOD1 (0.79) | NOD1PLA2G2CPLA2G10SLC6A5FAAH | |
| SCHEMBL6635175 | 1.00 | NOD1 (0.79) | NOD1PLA2G2CPLA2G10SLC6A5FAAH | |
| SCHEMBL20956609 | 1.00 | NOD1 (0.79) | NOD1PLA2G2CPLA2G10SLC6A5FAAH | |
| SCHEMBL20956606 | 1.00 | NOD1 (0.79) | NOD1PLA2G2CPLA2G10SLC6A5FAAH | |
| SCHEMBL20956594 | 1.00 | NOD1 (0.79) | NOD1PLA2G2CPLA2G10SLC6A5FAAH | |
| SCHEMBL20956593 | 1.00 | NOD1 (0.79) | NOD1PLA2G2CPLA2G10SLC6A5FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023106123-A1 | COSMETIC | 株式会社 資生堂 | 2023-06-15 | — | — | WO | disclosed |
| WO-2022210147-A1 | COSMETIC | 株式会社 資生堂 | 2022-10-06 | — | — | WO | disclosed |
| WO-2022210146-A1 | COSMETIC PREPARATION | 株式会社 資生堂 | 2022-10-06 | — | — | WO | disclosed |
| WO-2022210148-A1 | COSMETIC PREPARATION | 株式会社 資生堂 | 2022-10-06 | — | — | WO | disclosed |
| WO-2021049483-A1 | POWDER SURFACE TREATMENT METHOD, SURFACE TREATING AGENT COMPOSITION USED THEREFOR, AND SURFACE-TREATED POWDER | 味の素株式会社 | 2021-03-18 | — | — | WO | disclosed |
| CN-111372552-A | Customized cosmetic kit | 株式会社资生堂 | 2020-07-03 | — | — | CN | disclosed |
| EP-1688126-B1 | GLYCYLGLYCINE AS PARAKERATOSIS INHIBITOR | SHISEIDO CO LTD (JP) | 2017-08-23 | — | — | EP | disclosed |
| US-8586638-B2 | Parakeratosis inhibitor and skin preparation for external use | SHISEIDO COMPANY, LTD (JP) | 2013-11-19 | — | — | US | disclosed |
| EP-2583664-A1 | SKIN IMPROVING DERMO-COSMETICS | SHISEIDO COMPANY, LTD. (JP) | 2013-04-24 | — | — | EP | disclosed |
| US-20130079368-A1 | SKIN IMPROVING DERMO-COSMETICS | SHISEIDO COMPANY, LTD. (JP) | 2013-03-28 | — | — | US | disclosed |
| EP-2491980-A2 | Parakeratosis inhibitor and skin preparation for external use | SHISEIDO COMPANY LIMITED (JP) | 2012-08-29 | — | — | EP | disclosed |
| EP-2491981-A2 | Parakeratosis inhibitor and external composition for skin | SHISEIDO COMPANY LIMITED (JP) | 2012-08-29 | — | — | EP | disclosed |
| US-20120053243-A1 | PARAKERATOSIS INHIBITOR AND SKIN PREPARATION FOR EXTERNAL USE | SHISEIDO COMPANY, LTD. (JP) | 2012-03-01 | — | — | US | disclosed |
| US-20070225380-A1 | Parakeratosis Inhibitor and Skin Preparation for External use | SHISEIDO COMPANY LTD. (JP) | 2007-09-27 | — | — | US | disclosed |
| EP-1688126-A1 | PARAKERATOSIS INHIBITOR AND EXTERNAL COMPOSITION FOR SKIN | SHISEIDO COMPANY LIMITED (JP) | 2006-08-09 | — | — | EP | disclosed |
| US-5866158-A | STORAGE STABILITY | L'OREAL (FR) | 1999-02-02 | — | — | US | disclosed |
| US-5741518-A | Composition composed of an aqueous dispersion of stabilized vesicles of nonionic amphiphilic lipids | L'OREAL (FR) | 1998-04-21 | — | — | US | disclosed |
| EP-0348091-B1 | Aerosol composition | SHISEIDO CO LTD (JP) | 1994-01-12 | — | — | EP | disclosed |
| US-5223244-A | Undissolved composite powder with polymer core and attached sheath, non-chlorofluorocarbon propellant | SHISEIDO COMPANY, LTD. (JP) | 1993-06-29 | — | — | US | disclosed |
| EP-0348091-A1 | Aerosol composition | SHISEIDO COMPANY LIMITED (JP) | 1989-12-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120053243-A1 | PARAKERATOSIS INHIBITOR AND SKIN PREPARATION FOR EXTERNAL USE | CUTA, HPN, DNPEP | NOD1 2051/4885PLA2G2C 2789/4885PLA2G10 1022/4885 |
| US-20070225380-A1 | Parakeratosis Inhibitor and Skin Preparation for External use | CUTA, HPN, DNPEP | NOD1 2051/4885PLA2G2C 2789/4885PLA2G10 1022/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.