Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.65 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.65 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.62 |
| ▸ | RXRA | P19793 | 4/20 | 0.57 |
| ▸ | RXRB | P28702 | 3/20 | 0.57 |
| ▸ | RXRG | P48443 | 2/20 | 0.57 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.56 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.55 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.55 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.55 |
| ▸ | XDH | P47989 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5307725 | 0.91 | MRGPRX4 (0.76) | PPARANR4A2MRGPRX4RXRAPTPN7 | |
| SCHEMBL4428716 | 0.89 | NR4A2 (0.63) | PPARANR4A2MRGPRX4RXRARXRB | |
| SCHEMBL29556736 | 0.85 | MRGPRX4 (0.62) | NR4A2MRGPRX4RXRARXRBRXRG | |
| SCHEMBL1600077 | 0.85 | MRGPRX4 (0.62) | NR4A2MRGPRX4RXRARXRBRXRG | |
| SCHEMBL17916639 | 0.84 | NR4A2 (0.60) | PPARANR4A2MRGPRX4RXRARXRB | |
| Hydrochloric Acid SCHEMBL10857748 | 0.84 | MRGPRX4 (0.61) | NR4A2MRGPRX4RXRARXRBRXRG | |
| SCHEMBL25216997 | 0.83 | XDH (0.66) | PPARANR4A2MRGPRX4PTGER1PTPN7 | |
| SCHEMBL7516329 | 0.82 | NR4A2 (0.55) | PPARANR4A2MRGPRX4PTGER1NPC1 | |
| SCHEMBL7469360 | 0.82 | MRGPRX4 (0.71) | PPARAMRGPRX4RXRAPTGER1HPGD | |
| SCHEMBL29556803 | 0.82 | MRGPRX4 (0.71) | PPARAMRGPRX4RXRAPTGER1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6528655-B1 | Hydroxyphenyl diamido derivatives | PHARMACOR, INC. (CA) | 2003-03-04 | — | — | US | disclosed |
| WO-2002026697-A2 | AROMATIC DERIVATIVES WITH HIV INTEGRASE INHIBITORY PROPERTIES | PHARMACOR, INC. (CA) | 2002-04-04 | — | — | WO | disclosed |