Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 5/20 | 0.77 |
| ▸ | FAAH | O00519 | 4/20 | 0.61 |
| ▸ | BCHE | P06276 | 1/20 | 0.55 |
| ▸ | LIPC | P11150 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.55 |
| ▸ | LIPE | Q05469 | 1/20 | 0.55 |
| ▸ | ABHD16A | O95870 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6551376 | 0.87 | MGLL (1.00) | MGLLFAAHBCHELIPCACHE | |
| SCHEMBL6552675 | 0.84 | MGLL (1.00) | MGLLFAAHBCHELIPCACHE | |
| SCHEMBL7044274 | 0.82 | MGLL (0.53) | MGLLFAAHBCHELIPCACHE | |
| SCHEMBL2855348 | 0.79 | MGLL (0.71) | MGLLFAAHBCHELIPCACHE | |
| SCHEMBL7044899 | 0.78 | MGLL (0.59) | MGLLFAAHLIPCLIPEABHD16A | |
| SCHEMBL6552566 | 0.76 | MGLL (1.00) | MGLLFAAHABHD16A | |
| SCHEMBL9553638 | 0.73 | MGLL (0.60) | MGLLFAAHBCHELIPCACHE | |
| SCHEMBL2701979 | 0.72 | MGLL (0.61) | MGLLFAAHBCHELIPCACHE | |
| SCHEMBL6552790 | 0.72 | MGLL (0.74) | MGLLFAAHBCHELIPCACHE | |
| SCHEMBL7044238 | 0.72 | BCHE (0.81) | MGLLFAAHBCHELIPCACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1214302-B1 | SUBSTITUTED 3-PHENYL-5-ALKOXI-1,3,4-OXDIAZOL-2-ONES AND THEIR USE AS LIPASE INHIBITORS | AVENTIS PHARMA GMBH (DE) | 2003-10-29 | — | — | EP | disclosed |
| US-6596742-B1 | Inhibitory effect on the hormone-sensitive lipase, HSL. insecticides, controlling metabolism and multistage synthesis | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2003-07-22 | — | — | US | disclosed |
| EP-1214302-A1 | SUBSTITUTED 3-PHENYL-5-ALKOXI-1,3,4-OXDIAZOL-2-ONES AND THEIR USE AS LIPASE INHIBITORS | Aventis Pharma Deutschland GmbH (DE) | 2002-06-19 | — | — | EP | disclosed |
| WO-2001017981-A1 | SUBSTITUTED 3-PHENYL-5-ALKOXI-1,3,4-OXDIAZOL-2-ONES AND THEIR USE AS LIPASE INHIBITORS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-03-15 | — | — | WO | disclosed |