SCHEMBL7044899

SCHEMBL7044899

CC(C)Oc1nn(-c2ccc(Oc3ccc(Cl)cc3)cc2)c(=O)o1

nearest known ligand 0.67

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 3/20 0.59
FAAH O00519 1/20 0.59
NPBWR1 P48145 3/20 0.47
MCHR1 Q99705 1/20 0.47
ABHD16A O95870 1/20 0.47
LPL P06858 1/20 0.41
LIPC P11150 1/20 0.41
LIPE Q05469 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7044439 0.86 MGLL (0.78) MGLLFAAHNPBWR1ABHD16ALPL
SCHEMBL2853266 0.83 MGLL (0.64) MGLLFAAHNPBWR1MCHR1ABHD16A
SCHEMBL2854103 0.80 FAAH (0.53) MGLLFAAHNPBWR1MCHR1ABHD16A
SCHEMBL7046480 0.79 ABHD16A (0.50) MGLLFAAHNPBWR1MCHR1ABHD16A
SCHEMBL2233406 0.79 ABHD16A (0.72) MGLLFAAHNPBWR1ABHD16ALPL
SCHEMBL2702430 0.78 MGLL (0.52) MGLLFAAHNPBWR1ABHD16ALIPC
SCHEMBL7152190 0.78 MGLL (0.77) MGLLFAAHABHD16ALIPCLIPE
SCHEMBL6552566 0.74 MGLL (1.00) MGLLFAAHABHD16A
SCHEMBL7046287 0.72 MGLL (0.57) MGLLFAAHNPBWR1ABHD16A
SCHEMBL6552640 0.72 MGLL (0.43) MGLLFAAHABHD16ALPLLIPC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030236288-A1 Use of substituted 3-phenyl-5-alkoxy-3H-(1,3,4)-oxadizol-2-ones for inhibiting pancreatic lipase AVENTIS PHARMA DEUTSCHLAND GMBH 2003-12-25 US disclosed
US-6596742-B1 Inhibitory effect on the hormone-sensitive lipase, HSL. insecticides, controlling metabolism and multistage synthesis AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2003-07-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030236288-A1 Use of substituted 3-phenyl-5-alkoxy-3H-(1,3,4)-oxadizol-2-ones for inhibiting pancreatic lipase PNLIP, CEL, LIPE MGLL 10/4885FAAH 142/4885NPBWR1 380/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.