Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 3/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | MRGPRX1 | Q96LB2 | 7/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 3/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.40 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6300848 | 0.93 | F10 (0.47) | F10SLC6A4SLC6A2SLC6A3MRGPRX1 | |
| Trifluoroacetic Acid SCHEMBL7152732 | 0.86 | F10 (0.47) | F10SLC6A4SLC6A2SLC6A3MRGPRX1 | |
| SCHEMBL7156678 | 0.84 | PRSS1 (0.59) | F10MRGPRX1F2PRSS1PRSS2 | |
| Trifluoroacetic Acid SCHEMBL7154799 | 0.83 | F10 (0.49) | F10SLC6A4SLC6A2SLC6A3MRGPRX1 | |
| SCHEMBL6300739 | 0.82 | F10 (0.45) | F10BRD4F2PRSS1PRSS2 | |
| SCHEMBL7153138 | 0.79 | PRSS1 (0.38) | F10MRGPRX1F2PRSS1PRSS2 | |
| Trifluoroacetic Acid SCHEMBL6300672 | 0.79 | F10 (0.48) | F10F2 | |
| Trifluoroacetic Acid SCHEMBL7153335 | 0.77 | BRD4 (0.51) | F10SLC6A4SLC6A2SLC6A3MRGPRX1 | |
| SCHEMBL7157238 | 0.76 | PGR (0.41) | F10MRGPRX1 | |
| SCHEMBL8506821 | 0.76 | F10 (0.52) | F10MRGPRX1BRD4F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1312602-A1 | Amidino derivatives, and anticoagulants and thrombosis therapeutic agents containing them | Eisai Co., Ltd. (JP) | 2003-05-21 | — | — | EP | disclosed |