Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CTSA | P10619 | 2/20 | 0.36 |
| ▸ | EPHB3 | P54753 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 7/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2868090 | 0.83 | KMT2A (0.46) | ENPP2 | |
| SCHEMBL2872445 | 0.74 | KMT2A (0.43) | ENPP2 | |
| SCHEMBL2866051 | 0.68 | CRHR1 (0.44) | — | |
| SCHEMBL29070125 | 0.68 | PTPN11 (0.43) | CDC7DBF4CTSA | |
| SCHEMBL2868075 | 0.67 | KMT2A (0.43) | — | |
| SCHEMBL2871668 | 0.67 | CNR1 (0.44) | CDC7DBF4 | |
| SCHEMBL2872433 | 0.64 | CRHR1 (0.39) | ENPP2 | |
| SCHEMBL6049489 | 0.60 | HEXA (0.62) | TP53 | |
| SCHEMBL20400094 | 0.60 | ALOX15 (0.43) | CDC7DBF4CTSANUDT1 | |
| SCHEMBL665304 | 0.59 | MEN1 (0.69) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1364952-A1 | BICYCLIC NITROGENOUS FUSED-RING COMPOUND | Eisai Co., Ltd. (JP) | 2003-11-26 | — | — | EP | disclosed |