Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 10/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.48 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.48 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.48 |
| ▸ | DDB1 | Q16531 | 8/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinimide SCHEMBL27849600 | 0.82 | CRBN (0.79) | CRBNNPC1MAPK13MAPK12MAPK11 | |
| Succinimide SCHEMBL28635055 | 0.82 | CRBN (0.79) | CRBNNPC1MAPK13MAPK12MAPK11 | |
| Biphenyl SCHEMBL7154019 | 0.80 | CRBN (0.58) | CRBNLMNANPC1MAPK13MAPK12 | |
| Succinimide SCHEMBL28715844 | 0.76 | CRBN (0.52) | CRBNALOX12NPC1MAPK13MAPK12 | |
| Toluene SCHEMBL564059 | 0.76 | — | — | |
| SCHEMBL23142732 | 0.74 | CRBN (0.81) | CRBNALOX12NPC1DDB1MAPT | |
| Diphenylsulfane SCHEMBL4855555 | 0.74 | CRBN (0.50) | CRBNNPC1MAPK13MAPK12MAPK11 | |
| (Z)-1,2-Diphenylethene SCHEMBL10997055 | 0.74 | CRBN (0.50) | CRBNLMNANPC1MAPK13MAPK12 | |
| (Z)-1,2-Diphenylethene SCHEMBL10997053 | 0.74 | CRBN (0.50) | CRBNLMNANPC1MAPK13MAPK12 | |
| Succinimide SCHEMBL28472780 | 0.74 | CRBN (0.50) | CRBNLMNATSHRNPC1MAPK13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999059721-A1 | CATALYTIC ASYMMETRIC HYDROGENATION, HYDROFORMYLATION, AND HYDROVINYLATION VIA TRANSITION METAL CATALYSTS WITH PHOSPHINES AND PHOSPHITES | THE PENN STATE RESEARCH FOUNDATION (US) | 1999-11-25 | — | — | WO | disclosed |