Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KISS1R | Q969F8 | 10/20 | 0.61 |
| ▸ | GHSR | Q92847 | 2/20 | 0.60 |
| ▸ | NPY2R | P49146 | 1/20 | 0.60 |
| ▸ | IL23R | Q5VWK5 | 8/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7154208 | 1.00 | KISS1R (0.61) | KISS1RGHSRNPY2RIL23R | |
| SCHEMBL7155308 | 0.96 | IL23R (0.58) | KISS1RGHSRNPY2RIL23R | |
| SCHEMBL7174332 | 0.94 | IL23R (0.57) | KISS1RGHSRNPY2RIL23R | |
| SCHEMBL7174314 | 0.94 | IL23R (0.57) | KISS1RGHSRNPY2RIL23R | |
| SCHEMBL7153463 | 0.93 | KISS1R (0.57) | KISS1RGHSRNPY2RIL23R | |
| SCHEMBL7151611 | 0.92 | IL23R (0.62) | GHSRNPY2RIL23R | |
| SCHEMBL7154343 | 0.91 | KISS1R (0.56) | KISS1RGHSRNPY2RIL23R | |
| SCHEMBL7154339 | 0.91 | KISS1R (0.56) | KISS1RGHSRNPY2RIL23R | |
| SCHEMBL29641180 | 0.90 | GHSR (0.58) | GHSRNPY2R | |
| SCHEMBL9551262 | 0.90 | IL23R (0.61) | KISS1RGHSRNPY2RIL23R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030144211-A1 | Peptide inhibitors of inflammation mediated by selectins | CENTOCOR, INC. | 2003-07-31 | — | — | US | disclosed |
| US-6528487-B1 | Including GMP-140, ELAM-1, and lymphocyte-homing receptor. | CENTOCOR, INC. | 2003-03-04 | — | — | US | disclosed |
| EP-0608260-A1 | PEPTIDE INHIBITORS OF INFLAMMATION MEDIATED BY SELECTINS | CENTOCOR, INC. (US) | 1994-08-03 | — | — | EP | disclosed |
| WO-1993005070-A1 | PEPTIDE INHIBITORS OF INFLAMMATION MEDIATED BY SELECTINS | CENTOCOR, INC. (US) | 1993-03-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030144211-A1 | Peptide inhibitors of inflammation mediated by selectins | SELL, SELPLG, ELANE | KISS1R 3013/4885GHSR 705/4885NPY2R 2221/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.