Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS11D | O60235 | 12/20 | 0.50 |
| ▸ | F2 | P00734 | 4/20 | 0.48 |
| ▸ | F10 | P00742 | 3/20 | 0.48 |
| ▸ | PLG | P00747 | 3/20 | 0.48 |
| ▸ | FKBP1A | P62942 | 5/20 | 0.47 |
| ▸ | PRCP | P42785 | 1/20 | 0.46 |
| ▸ | XIAP | P98170 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7155123 | 0.92 | TMPRSS11D (0.47) | TMPRSS11DF2F10PLGFKBP1A | |
| SCHEMBL7451955 | 0.88 | F2 (0.55) | TMPRSS11DF2F10PLGXIAP | |
| SCHEMBL7154250 | 0.88 | TMPRSS11D (0.47) | TMPRSS11DF2F10PLGFKBP1A | |
| Hydrochloric Acid SCHEMBL7414559 | 0.88 | F2 (0.54) | TMPRSS11DF2F10PLGXIAP | |
| SCHEMBL7102494 | 0.87 | TMPRSS11D (0.58) | TMPRSS11DF2F10PLGFKBP1A | |
| SCHEMBL7102558 | 0.85 | TMPRSS11D (0.52) | TMPRSS11DF2F10PLG | |
| SCHEMBL7338542 | 0.85 | F2 (0.54) | TMPRSS11DF2F10PLG | |
| SCHEMBL7106028 | 0.85 | TMPRSS11D (0.68) | TMPRSS11DF2F10PLG | |
| SCHEMBL6971395 | 0.85 | F2 (0.59) | F2F10PLG | |
| SCHEMBL7350464 | 0.85 | F2 (0.59) | F2F10PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6534536-B1 | Alkylsulfonamido heterocyclic thrombin inhibitors | BRISTOL-MYERS SQUIBB COMPANY | 2003-03-18 | — | — | US | claimed |