Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS11D | O60235 | 8/20 | 0.47 |
| ▸ | FKBP1A | P62942 | 7/20 | 0.47 |
| ▸ | F2 | P00734 | 4/20 | 0.46 |
| ▸ | F10 | P00742 | 1/20 | 0.46 |
| ▸ | PLG | P00747 | 1/20 | 0.46 |
| ▸ | XIAP | P98170 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7154243 | 0.92 | TMPRSS11D (0.50) | TMPRSS11DFKBP1AF2F10PLG | |
| SCHEMBL7446078 | 0.88 | F2 (0.56) | F2F10PLGXIAP | |
| SCHEMBL7155126 | 0.88 | FKBP1A (0.46) | TMPRSS11DFKBP1AF2 | |
| Hydrochloric Acid SCHEMBL7414568 | 0.87 | F2 (0.55) | F2F10PLGXIAP | |
| SCHEMBL7350464 | 0.85 | F2 (0.59) | F2F10PLG | |
| SCHEMBL6971395 | 0.85 | F2 (0.59) | F2F10PLG | |
| SCHEMBL7343558 | 0.84 | DPP4 (0.53) | FKBP1AF2 | |
| SCHEMBL7343548 | 0.84 | DPP4 (0.53) | FKBP1AF2 | |
| SCHEMBL7346744 | 0.84 | F2 (0.54) | TMPRSS11DF2F10PLG | |
| SCHEMBL7402728 | 0.83 | ACE (0.55) | TMPRSS11DFKBP1AF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6534536-B1 | Alkylsulfonamido heterocyclic thrombin inhibitors | BRISTOL-MYERS SQUIBB COMPANY | 2003-03-18 | — | — | US | claimed |
| EP-0601459-A2 | Sulfonamido heterocyclic thrombin inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 1994-06-15 | — | — | EP | claimed |
| US-6534536-B1 | Alkylsulfonamido heterocyclic thrombin inhibitors | BRISTOL-MYERS SQUIBB COMPANY | 2003-03-18 | — | — | US | disclosed |
| US-5583146-A | Heterocyclic thrombin inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-12-10 | — | — | US | disclosed |
| EP-0601459-A2 | Sulfonamido heterocyclic thrombin inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 1994-06-15 | — | — | EP | disclosed |