Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 2/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.49 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.49 |
| ▸ | F2 | P00734 | 11/20 | 0.49 |
| ▸ | TMPRSS6 | Q8IU80 | 8/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | BCL2 | P10415 | 1/20 | 0.45 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.45 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.45 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 2/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | F7 | P08709 | 1/20 | 0.43 |
| ▸ | F3 | P13726 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7158131 | 0.89 | F2 (0.48) | PRSS1PRSS2PRSS3ST14F2 | |
| Trifluoroacetic Acid SCHEMBL7157168 | 0.88 | MGAT2 (0.50) | PRSS1PRSS2PRSS3ST14F2 | |
| Trifluoroacetic Acid SCHEMBL7156674 | 0.87 | PRSS1 (0.61) | PRSS1PRSS2PRSS3ST14F2 | |
| Trifluoroacetic Acid SCHEMBL7150783 | 0.85 | PRSS1 (0.58) | PRSS1PRSS2PRSS3ST14F2 | |
| Trifluoroacetic Acid SCHEMBL7154599 | 0.84 | F10 (0.43) | PRSS1PRSS2PRSS3F2TMPRSS6 | |
| Trifluoroacetic Acid SCHEMBL7150780 | 0.84 | PRSS1 (0.55) | PRSS1PRSS2PRSS3ST14F2 | |
| Trifluoroacetic Acid SCHEMBL7154637 | 0.82 | F2 (0.40) | PRSS1PRSS2PRSS3F2TMPRSS6 | |
| Trifluoroacetic Acid SCHEMBL7155335 | 0.82 | F2 (0.56) | PRSS1PRSS2PRSS3ST14F2 | |
| SCHEMBL6295991 | 0.81 | PRSS1 (0.68) | PRSS1PRSS2PRSS3ST14F2 | |
| Trifluoroacetic Acid SCHEMBL7157233 | 0.79 | PRSS1 (0.55) | PRSS1PRSS2PRSS3ST14F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1312602-A1 | Amidino derivatives, and anticoagulants and thrombosis therapeutic agents containing them | Eisai Co., Ltd. (JP) | 2003-05-21 | — | — | EP | disclosed |