Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 11/20 | 0.56 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.56 |
| ▸ | F3 | P13726 | 15/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
| ▸ | F7 | P08709 | 3/20 | 0.50 |
| ▸ | F10 | P00742 | 2/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.50 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7150780 | 0.93 | PRSS1 (0.55) | F2TMPRSS6F3MEN1ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL7156674 | 0.91 | PRSS1 (0.61) | F2TMPRSS6F3MEN1ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL7157181 | 0.90 | F3 (0.50) | F2F3F7F10PRSS1 | |
| Trifluoroacetic Acid SCHEMBL7150783 | 0.89 | PRSS1 (0.58) | F2TMPRSS6F3MEN1ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL7154700 | 0.88 | ALDH1A1 (0.58) | F2F3ALDH1A1F7F10 | |
| Trifluoroacetic Acid SCHEMBL7157233 | 0.86 | PRSS1 (0.55) | F2TMPRSS6F3MEN1ALDH1A1 | |
| SCHEMBL6295991 | 0.86 | PRSS1 (0.68) | F2TMPRSS6MEN1ALDH1A1KMT2A | |
| Trifluoroacetic Acid SCHEMBL7151193 | 0.85 | PRSS1 (0.51) | F2TMPRSS6F3MEN1ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL7158701 | 0.84 | F2 (0.53) | F2F3MEN1ALDH1A1KMT2A | |
| Trifluoroacetic Acid SCHEMBL7150667 | 0.83 | PGR (0.48) | F2TMPRSS6F3ALDH1A1F7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1312602-A1 | Amidino derivatives, and anticoagulants and thrombosis therapeutic agents containing them | Eisai Co., Ltd. (JP) | 2003-05-21 | — | — | EP | disclosed |