Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 3/20 | 0.55 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.55 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.55 |
| ▸ | ST14 | Q9Y5Y6 | 3/20 | 0.55 |
| ▸ | F2 | P00734 | 7/20 | 0.51 |
| ▸ | TMPRSS6 | Q8IU80 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | PLA2G7 | Q13093 | 3/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | F10 | P00742 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.43 |
| ▸ | F3 | P13726 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7150780 | 0.93 | PRSS1 (0.55) | PRSS1PRSS2PRSS3ST14F2 | |
| Trifluoroacetic Acid SCHEMBL7154050 | 0.91 | F2 (0.53) | PRSS1PRSS2PRSS3ST14F2 | |
| Trifluoroacetic Acid SCHEMBL7148990 | 0.90 | PLA2G7 (0.46) | PRSS1PRSS2PRSS3ST14F2 | |
| Trifluoroacetic Acid SCHEMBL7153324 | 0.90 | F2 (0.48) | PRSS1PRSS2PRSS3ST14F2 | |
| Trifluoroacetic Acid SCHEMBL7151193 | 0.90 | PRSS1 (0.51) | PRSS1PRSS2PRSS3ST14F2 | |
| Trifluoroacetic Acid SCHEMBL7156674 | 0.88 | PRSS1 (0.61) | PRSS1PRSS2PRSS3ST14F2 | |
| Trifluoroacetic Acid SCHEMBL7155335 | 0.86 | F2 (0.56) | PRSS1PRSS2PRSS3ST14F2 | |
| Trifluoroacetic Acid SCHEMBL7150783 | 0.86 | PRSS1 (0.58) | PRSS1PRSS2PRSS3ST14F2 | |
| Trifluoroacetic Acid SCHEMBL7153962 | 0.85 | F2 (0.51) | PRSS1PRSS2PRSS3ST14F2 | |
| SCHEMBL6294700 | 0.84 | PRSS1 (0.55) | PRSS1PRSS2PRSS3ST14F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1312602-A1 | Amidino derivatives, and anticoagulants and thrombosis therapeutic agents containing them | Eisai Co., Ltd. (JP) | 2003-05-21 | — | — | EP | disclosed |