Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G7 | Q13093 | 3/20 | 0.45 |
| ▸ | F2 | P00734 | 3/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.42 |
| ▸ | ST14 | Q9Y5Y6 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TCF4 | P15884 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 4/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7155329 | 0.93 | F2 (0.47) | PLA2G7F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7151200 | 0.93 | PRSS1 (0.50) | PLA2G7F2PRSS1PRSS2PRSS3 | |
| Trifluoroacetic Acid SCHEMBL7154778 | 0.90 | PLA2G7 (0.46) | PLA2G7F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6300739 | 0.89 | F10 (0.45) | PLA2G7F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6294964 | 0.89 | F2 (0.48) | PLA2G7F2PRSS1PRSS2PRSS3 | |
| Trifluoroacetic Acid SCHEMBL7158686 | 0.85 | F2 (0.45) | PLA2G7F2PRSS1PRSS2PRSS3 | |
| Trifluoroacetic Acid SCHEMBL7155325 | 0.84 | F2 (0.47) | PLA2G7F2PRSS1PRSS2PRSS3 | |
| Trifluoroacetic Acid SCHEMBL7151193 | 0.83 | PRSS1 (0.51) | PLA2G7F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6300651 | 0.82 | PRSS1 (0.51) | PLA2G7F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6294700 | 0.81 | PRSS1 (0.55) | PLA2G7F2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1312602-A1 | Amidino derivatives, and anticoagulants and thrombosis therapeutic agents containing them | Eisai Co., Ltd. (JP) | 2003-05-21 | — | — | EP | disclosed |