Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR8 | P51685 | 1/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.69 |
| ▸ | MAPT | P10636 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14409545 | 0.92 | KDM4E (0.67) | CCR8ALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL14409539 | 0.87 | KDM4E (0.65) | CCR8ALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL608528 | 0.87 | ALDH1A1 (0.76) | CCR8ALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL7158829 | 0.86 | CCR8 (0.76) | CCR8ALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL6527959 | 0.86 | CCR8 (0.76) | CCR8ALDH1A1KDM4EMAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7438287 | 0.85 | ALDH1A1 (0.74) | CCR8ALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL6526874 | 0.83 | CCR8 (0.71) | CCR8ALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL6529304 | 0.83 | CCR8 (0.71) | CCR8ALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL654393 | 0.82 | ALDH1A1 (0.73) | CCR8ALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL6527241 | 0.82 | ALDH1A1 (0.73) | CCR8ALDH1A1KDM4EMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003037271-A2 | COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE THEREFOR | MILLENNIUM PHARMACEUTICALS,INC. (US) | 2003-05-08 | — | — | WO | disclosed |