SCHEMBL608528

SCHEMBL608528

CCOC(=O)C1CCN(Cc2ccccc2)CC1

nearest known ligand 0.85

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.76
CCR8 P51685 1/20 0.76
KDM4E B2RXH2 6/20 0.72
MAPT P10636 1/20 0.71
SMN1; SMN2 Q16637 2/20 0.70
KMT2A Q03164 1/20 0.67
PKM P14618 1/20 0.64
NPSR1 Q6W5P4 1/20 0.64
POLB P06746 1/20 0.64
TSHR P16473 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7438287 0.99 ALDH1A1 (0.74) ALDH1A1CCR8KDM4EMAPTSMN1; SMN2
SCHEMBL3317577 0.95 L3MBTL1 (0.71) ALDH1A1CCR8KDM4EMAPTSMN1; SMN2
SCHEMBL1545229 0.92 L3MBTL1 (0.74) ALDH1A1CCR8KDM4EMAPTSMN1; SMN2
SCHEMBL14022760 0.92 L3MBTL1 (0.74) ALDH1A1CCR8KDM4EMAPTSMN1; SMN2
SCHEMBL8263564 0.92 L3MBTL1 (0.74) ALDH1A1CCR8KDM4EMAPTSMN1; SMN2
SCHEMBL8791924 0.90 CCR8 (0.81) ALDH1A1CCR8KDM4EMAPTSMN1; SMN2
SCHEMBL4693375 0.89 L3MBTL1 (0.76) ALDH1A1CCR8KDM4EMAPTSMN1; SMN2
SCHEMBL22533378 0.89 ABL1 (0.62) ALDH1A1CCR8KDM4EMAPTSMN1; SMN2
SCHEMBL6527959 0.89 CCR8 (0.76) ALDH1A1CCR8KDM4EMAPTSMN1; SMN2
SCHEMBL7158829 0.89 CCR8 (0.76) ALDH1A1CCR8KDM4EMAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 390 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117924153-A Preparation method of key intermediate of donepezil bulk drug 山东盛安贝新材料有限公司南京分公司 2024-04-26 CN claimed
CN-115073358-B Preparation method of N-benzyl-4-ethyl piperidine formate 安徽德诺医药股份有限公司 2023-09-26 CN claimed
CN-115073358-A Preparation method of N-benzyl-4-ethyl piperidine formate 安徽德诺医药股份有限公司 2022-09-20 CN claimed
US-20050261343-A1 Anthranilamides and their use as pharmaceutical agents BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2005-11-24 US claimed
US-20040029880-A1 Anthranyl amides and their use as medicaments BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2004-02-12 US claimed
EP-4724435-A1 BIFUNCTIONAL AZINES CONJOGATES AS SELECTIVE DEGRADERS OF SMARCA2 AND THERAPEUTIC USES THEREOF Nurix Therapeutics, Inc. (US) 2026-04-15 EP disclosed
EP-4684837-A1 NOVEL MODULATORS OF THE 5-HYDROXYTRYPTAMINE RECEPTOR 7 AND THEIR METHOD OF USE Temple University of the Commonwealth System of Higher Education (US) 2026-01-28 EP disclosed
US-20250340560-A1 SUBSTITUTED PYRAZOLO[1,5-a]PYRIMIDINES AS BRUTON'S TYROSINE KINASE MODULATORS BEIGENE SWITZERLAND GMBH (CH) 2025-11-06 US disclosed
WO-2025201533-A1 NOVEL ACIDIC COMPOUNDS, COMPOSITIONS COMPRISING THE SAME AND USES THEREOF NUPHASE THERAPEUTICS (SHANGHAI) LIMITED., CO. (CN) 2025-10-02 WO disclosed
US-20250282790-A1 NOVEL MODULATORS OF THE 5-HYDROXYTRYPTAMINE RECEPTOR 7 AND THEIR METHOD OF USE PRAEVENTIX, LLC 2025-09-11 US disclosed
EP-3541790-B1 3-(2-(4-PHENYLPIPERAZIN-1-YL)ETHYL)-2-OXA-8-AZASPIRO[4.5]DECAN-1-ONE DERIVATIVES AND RELATED COMPOUNDS AS 5-HYDROXYTRYPTAMINE RECEPTOR 7 (5-HT7) MODULATORS FOR TREATING E.G. INFLAMMATORY BOWEL DISEASE, CIRCADIAN RHYTHM DISORDER OR DEPRESSION UNIV TEMPLE (US) 2025-09-03 EP disclosed
WO-2025137507-A1 SOS1 INHIBITORS AND USES THEREOF REGOR PHARMACEUTICALS, INC. (US) 2025-06-26 WO disclosed
EP-0291244-A1 Cyclic carbamate derivatives A.H. ROBINS COMPANY, INCORPORATED (a Delaware corporation) (US) 1988-11-17 EP disclosed
EP-0235463-A2 N-substituted-arylalkyl and arylalkylene piperidines as cardiovascular antihistaminic and antisecretory agents A.H. ROBINS COMPANY, INCORPORATED (a Delaware corporation) (US) 1987-09-09 EP disclosed
EP-0228893-A2 Arylalkyl-heterocyclic amines, n-substituted by aryloxyalkyl group in allergy treatment A.H. ROBINS COMPANY, INCORPORATED (a Delaware corporation) (US) 1987-07-15 EP disclosed
US-4581171-A ANTISEROTONINE AGENTS JANSSEN PHARMACEUTICA, N.V. (BE) 1986-04-08 US disclosed
EP-0156433-A2 Anti-virally active pyridazinamines JANSSEN PHARMACEUTICA N.V. (BE) 1985-10-02 EP disclosed
US-4533665-A SEROTONIN ANTAGONIST JANSSEN PHARMACEUTICA (BE) 1985-08-06 US disclosed
US-4485107-A SEDATIVES, MUSCLE RELAXANTS JANSSEN PHARMACEUTICA N.V. (BE) 1984-11-27 US disclosed
EP-0110435-A1 Novel ((bis(aryl)methylene)-1-piperidinyl)alkyl-pyrimidinones JANSSEN PHARMACEUTICA N.V. (BE) 1984-06-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050261343-A1 Anthranilamides and their use as pharmaceutical agents AADAC, ANTXR2, VEGFA ALDH1A1 1532/4885CCR8 2937/4885KDM4E 2859/4885
US-20250282790-A1 NOVEL MODULATORS OF THE 5-HYDROXYTRYPTAMINE RECEPTOR 7 AND THEIR METHOD OF USE HTR7, HTR5A, HTR6 ALDH1A1 2885/4885CCR8 1487/4885KDM4E 3032/4885
US-20040029880-A1 Anthranyl amides and their use as medicaments AADAC, ANTXR2, VEGFA ALDH1A1 1386/4885CCR8 3244/4885KDM4E 2736/4885
US-20250340560-A1 SUBSTITUTED PYRAZOLO[1,5-a]PYRIMIDINES AS BRUTON'S TYROSINE KINASE MODULATORS BTK, LCK, SYK ALDH1A1 3106/4885CCR8 3166/4885KDM4E 1852/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.