Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR8 | P51685 | 13/20 | 0.68 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | DRD4 | P21917 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6495888 | 0.89 | CCR8 (0.79) | CCR8SIGMAR1 | |
| SCHEMBL6504436 | 0.83 | CCR8 (0.81) | CCR8SIGMAR1KCNH2 | |
| SCHEMBL6505051 | 0.80 | CCR8 (0.54) | CCR8SIGMAR1 | |
| SCHEMBL6506018 | 0.80 | CCR8 (1.00) | CCR8SIGMAR1KCNH2 | |
| SCHEMBL3164487 | 0.80 | SIGMAR1 (0.74) | SIGMAR1DRD4 | |
| SCHEMBL7067262 | 0.79 | SIGMAR1 (0.55) | CCR8SIGMAR1KCNH2DRD4 | |
| SCHEMBL6505985 | 0.79 | CCR8 (0.83) | CCR8SIGMAR1KCNH2 | |
| SCHEMBL6497669 | 0.79 | CCR8 (1.00) | CCR8SIGMAR1KCNH2 | |
| SCHEMBL6501162 | 0.79 | CCR8 (0.82) | CCR8SIGMAR1KCNH2 | |
| SCHEMBL6507686 | 0.78 | CCR8 (0.80) | CCR8SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003037271-A2 | COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE THEREFOR | MILLENNIUM PHARMACEUTICALS,INC. (US) | 2003-05-08 | — | — | WO | disclosed |