Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | SMYD2 | Q9NRG4 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24312400 | 0.95 | CYP2D6 (0.38) | CYP2D6CYP3A4HTTSMN1; SMN2KMT2A | |
| SCHEMBL30335638 | 0.94 | CYP2D6 (0.34) | CYP2D6RIPK1CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL3834273 | 0.92 | SLC6A2 (0.36) | CYP2D6RIPK1CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL21873649 | 0.92 | CYP1A2 (0.42) | CYP2D6CYP3A4HTTSMN1; SMN2KMT2A | |
| SCHEMBL218117 | 0.92 | CYP1A2 (0.42) | CYP2D6CYP3A4HTTSMN1; SMN2KMT2A | |
| SCHEMBL2531862 | 0.92 | CYP1A2 (0.42) | CYP2D6CYP3A4HTTSMN1; SMN2KMT2A | |
| SCHEMBL28885790 | 0.91 | TRPA1 (0.36) | CYP2D6RIPK1CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL28885789 | 0.91 | TRPA1 (0.36) | CYP2D6RIPK1CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL6158503 | 0.90 | CYP3A4 (0.37) | CYP2D6CYP3A4HTTSMN1; SMN2KMT2A | |
| SCHEMBL9523633 | 0.90 | GAA (0.36) | CYP2D6CYP3A4HTTSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6632953-B1 | Metal complex comprising a phospholane as claimed in any of claim 1 and a central atom selected from the group of Rh, Ru, Ir, Pd, Pt, Ni. asymmetric hydrogenation of compounds by reacting the starting compounds to be hydrogenated with | BASF AKTIENGESELLSCHAFT (DE) | 2003-10-14 | — | — | US | disclosed |
| EP-0992481-B1 | Process for the asymmetric hydrogenation of beta-ketoesters | BASF AG (DE) | 2003-05-21 | — | — | EP | disclosed |
| EP-1082328-B1 | PRODUCTION OF OPTICALLY ACTIVE PHOSPHOLANES | BASF AG (DE) | 2002-11-20 | — | — | EP | disclosed |
| EP-0992481-A1 | Process for the asymmetric hydrogenation of beta-ketoesters | BASF AKTIENGESELLSCHAFT (DE) | 2000-04-12 | — | — | EP | disclosed |