Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMYD2 | Q9NRG4 | 2/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7155286 | 0.92 | CYP2D6 (0.37) | SLC6A2SLC6A4SLC6A3CYP2D6SMN1; SMN2 | |
| SCHEMBL15209484 | 0.88 | ALOX15 (0.44) | SLC6A2SLC6A4SLC6A3ALOX15CYP2D6 | |
| SCHEMBL15209482 | 0.88 | ALOX15 (0.44) | SLC6A2SLC6A4SLC6A3ALOX15CYP2D6 | |
| SCHEMBL24312400 | 0.88 | CYP2D6 (0.38) | SLC6A2SLC6A4SLC6A3CYP2D6SMN1; SMN2 | |
| SCHEMBL30335638 | 0.87 | CYP2D6 (0.34) | CYP2D6SMN1; SMN2CYP3A4HTTKMT2A | |
| SCHEMBL21873649 | 0.84 | CYP1A2 (0.42) | CYP2D6SMN1; SMN2CYP3A4HTTKMT2A | |
| SCHEMBL218117 | 0.84 | CYP1A2 (0.42) | CYP2D6SMN1; SMN2CYP3A4HTTKMT2A | |
| SCHEMBL2531862 | 0.84 | CYP1A2 (0.42) | CYP2D6SMN1; SMN2CYP3A4HTTKMT2A | |
| SCHEMBL28885789 | 0.84 | TRPA1 (0.36) | SLC6A2SLC6A4SLC6A3CYP2D6SMN1; SMN2 | |
| SCHEMBL28885790 | 0.84 | TRPA1 (0.36) | SLC6A2SLC6A4SLC6A3CYP2D6SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090312310-A1 | Imidazothiazole derivatives | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2009-12-17 | — | — | US | disclosed |
| US-20090312310-A1 | Imidazothiazole derivatives | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2009-12-17 | — | — | US | disclosed |
| EP-2103619-A1 | IMIDAZOTHIAZOLE DERIVATIVES | Daiichi Sankyo Company, Limited (JP) | 2009-09-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090312310-A1 | Imidazothiazole derivatives | TP53, MDM2, TP53BP1 | SLC6A2 4884/4885SLC6A4 4784/4885SLC6A3 4833/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.