Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.37 |
| ▸ | EP300 | Q09472 | 1/20 | 0.36 |
| ▸ | SPHK2 | Q9NRA0 | 4/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | CETP | P11597 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | GMNN | O75496 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | CXCR5 | P32302 | 2/20 | 0.34 |
| ▸ | CCR6 | P51684 | 2/20 | 0.34 |
| ▸ | BLM | P54132 | 2/20 | 0.34 |
| ▸ | UBE2N | P61088 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3821504 | 0.92 | EP300 (0.47) | EP300SPHK2SPHK1MEN1MAPT | |
| SCHEMBL27885364 | 0.86 | OR51E2 (0.35) | GRIK1OR51E2 | |
| SCHEMBL5598165 | 0.77 | — | — | |
| SCHEMBL30444755 | 0.77 | — | — | |
| SCHEMBL6635066 | 0.75 | GPR84 (0.53) | EP300GPR84FFAR1 | |
| Water SCHEMBL27476748 | 0.75 | OR51E2 (0.42) | OR51E2 | |
| SCHEMBL27557548 | 0.73 | OR51E2 (0.35) | OR51E2 | |
| SCHEMBL14563972 | 0.71 | — | — | |
| SCHEMBL13655829 | 0.70 | SPHK1 (0.54) | EP300SPHK2SPHK1MEN1MAPT | |
| SCHEMBL1134639 | 0.70 | SPHK1 (0.54) | EP300SPHK2SPHK1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1066235-B1 | SYNTHETIC ENDOGENOUS CANNABINOID ANALOGUES AND USES THEREOF | YISSUM RES DEV CO (IL) | 2003-10-01 | — | — | EP | claimed |