Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 7/20 | 0.54 |
| ▸ | SPHK2 | Q9NRA0 | 6/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.54 |
| ▸ | CETP | P11597 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | GMNN | O75496 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | BLM | P54132 | 3/20 | 0.54 |
| ▸ | UBE2N | P61088 | 3/20 | 0.54 |
| ▸ | GLA | P06280 | 2/20 | 0.54 |
| ▸ | THRB | P10828 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | CXCR5 | P32302 | 2/20 | 0.54 |
| ▸ | CCR6 | P51684 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | THPO | P40225 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1134639 | 1.00 | SPHK1 (0.54) | SPHK1SPHK2MAPTCYP2D6CETP | |
| SCHEMBL13685823 | 1.00 | SPHK1 (0.54) | SPHK1SPHK2MAPTCYP2D6CETP | |
| SCHEMBL28051143 | 1.00 | SPHK1 (0.54) | SPHK1SPHK2MAPTCYP2D6CETP | |
| SCHEMBL13571503 | 0.83 | SPHK1 (0.54) | SPHK1SPHK2MAPTCYP2D6CETP | |
| SCHEMBL13571502 | 0.83 | SPHK1 (0.54) | SPHK1SPHK2MAPTCYP2D6CETP | |
| SCHEMBL13571254 | 0.83 | SPHK1 (0.54) | SPHK1SPHK2MAPTCYP2D6CETP | |
| SCHEMBL7728491 | 0.83 | SPHK1 (0.54) | SPHK1SPHK2MAPTCYP2D6CETP | |
| SCHEMBL13571253 | 0.83 | SPHK1 (0.54) | SPHK1SPHK2MAPTCYP2D6CETP | |
| SCHEMBL3821504 | 0.78 | EP300 (0.47) | SPHK1SPHK2MAPTCYP2D6CETP | |
| SCHEMBL26187567 | 0.71 | EP300 (0.44) | MAPTKMT2AGMNNLMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8357381-B2 | Dispersions comprising acylglutamates | COGNIS IP MANAGEMENT GMBH (DE) | 2013-01-22 | — | — | US | disclosed |
| US-20090258043-A1 | Dispersions Comprising Acylglutamates | COGNIS IP MANAGEMENT GMBH (DE) | 2009-10-15 | — | — | US | disclosed |
| US-20080166308-A1 | Tanning Method | MERCK PATENT GESELLSCHAFT (DE) | 2008-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090258043-A1 | Dispersions Comprising Acylglutamates | ACAT2, GATD3, GGCT | SPHK1 3930/4885SPHK2 4113/4885MAPT 1643/4885 |
| US-20080166308-A1 | Tanning Method | TES, TYR, CUTA | SPHK1 3932/4885SPHK2 4354/4885MAPT 1759/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.