Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 6/20 | 0.53 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.44 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5729723 | 0.82 | OPRM1 (0.48) | OPRM1OPRD1OPRK1HDAC4OPRL1 | |
| SCHEMBL31125559 | 0.81 | HDAC4 (0.59) | OPRM1OPRD1OPRK1HDAC4OPRL1 | |
| SCHEMBL301133 | 0.81 | HDAC4 (0.59) | OPRM1OPRD1OPRK1HDAC4OPRL1 | |
| SCHEMBL503892 | 0.80 | OPRM1 (0.73) | OPRM1OPRD1OPRK1SLC22A1SLC6A4 | |
| SCHEMBL31580968 | 0.80 | HDAC4 (0.67) | HDAC4 | |
| SCHEMBL5637311 | 0.80 | HDAC4 (0.62) | OPRM1OPRD1OPRK1HDAC4OPRL1 | |
| SCHEMBL30501854 | 0.80 | HDAC4 (0.62) | OPRM1OPRD1OPRK1HDAC4OPRL1 | |
| SCHEMBL3184587 | 0.80 | HDAC4 (0.67) | HDAC4 | |
| SCHEMBL8044669 | 0.79 | OPRL1 (0.56) | OPRM1OPRD1OPRK1KDM4EOPRL1 | |
| SCHEMBL2867660 | 0.78 | HDAC4 (0.65) | HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003037271-A2 | COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE THEREFOR | MILLENNIUM PHARMACEUTICALS,INC. (US) | 2003-05-08 | — | — | WO | disclosed |