Saccharin

Saccharin

SCHEMBL7156459

C=CC(=O)O.O=C1NS(=O)(=O)c2ccccc21

nearest known ligand 0.73

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 6/20 0.73
CA9 Q16790 6/20 0.73
CA2 P00918 5/20 0.73
CA1 P00915 2/20 0.73
KDM4E B2RXH2 1/20 0.73
USP2 O75604 1/20 0.73
LMNA P02545 1/20 0.73
BCHE P06276 1/20 0.73
CA4 P22748 1/20 0.73
CA6 P23280 1/20 0.73
CA5A P35218 1/20 0.73
CA7 P43166 1/20 0.73
KMT2A Q03164 1/20 0.73
CA14 Q9ULX7 1/20 0.73
CA5B Q9Y2D0 1/20 0.73
ALDH1A1 P00352 2/20 0.52
ALPI P09923 5/20 0.49
ALPL P05186 4/20 0.49
HSD11B1 P28845 1/20 0.49
GAA P10253 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Saccharin SCHEMBL28045129 0.89 CA12 (0.92) CA12CA9CA2CA1KDM4E
Saccharin SCHEMBL28334570 0.88 CA12 (0.88) CA12CA9CA2CA1KDM4E
Saccharin SCHEMBL27898163 0.86 CA12 (0.79) CA12CA9CA2CA1KDM4E
Saccharin SCHEMBL8935949 0.86 CA12 (0.92) CA12CA9CA2CA1KDM4E
Saccharin SCHEMBL28120403 0.86 CA12 (0.92) CA12CA9CA2CA1KDM4E
Saccharin SCHEMBL29037506 0.86 CA12 (0.92) CA12CA9CA2CA1KDM4E
Saccharin SCHEMBL27905604 0.86 CA12 (0.92) CA12CA9CA2CA1KDM4E
Saccharin SCHEMBL588640 0.86 CA12 (1.00) CA12CA9CA2CA1KDM4E
Saccharin SCHEMBL29358404 0.86 CA12 (1.00) CA12CA9CA2CA1KDM4E
Saccharin SCHEMBL3816 0.86 CA12 (1.00) CA12CA9CA2CA1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230002653-A1 MICHAEL-ADDITION-HARDENING HYBRID SYSTEM FOR CHEMICAL FIXING TECHNOLOGY FISCHERWERKE GMBH & CO. KG (DE) 2023-01-05 US claimed
US-20220411680-A1 MICHAEL-ADDITION-HARDENING SYNTHETIC RESIN FOR CHEMICAL FIXING TECHNOLOGY FISCHERWERKE GMBH & CO. KG (DE) 2022-12-29 US claimed
EP-4069792-A1 MICHAEL REACTION-CURING HYBRID SYSTEM FOR USE IN CHEMICAL FASTENING TECHNOLOGY fischerwerke GmbH & Co. KG (DE) 2022-10-12 EP claimed
WO-2021110621-A1 MICHAEL REACTION-CURING HYBRID SYSTEM FOR USE IN CHEMICAL FASTENING TECHNOLOGY FISCHERWERKE GMBH & CO. KG (DE) 2021-06-10 WO claimed
WO-2021110622-A1 MICHAEL REACTION-CURING SYNTHETIC RESIN FOR USE IN CHEMICAL FASTENING TECHNOLOGY FISCHERWERKE GMBH & CO. KG (DE) 2021-06-10 WO claimed
US-6537576-B1 Biologically active composition BIOGLAN AB (SE) 2003-03-25 US claimed
CN-1033840-C Ultrasonic contrast medium and application for diagnosis treatment SCHERING AG (DE) 1997-01-22 CN claimed
CN-1035437-A Ultrasonic contrast agents and manufacture method thereof and the application in diagnoses and treatment SCHERING AG (DE) 1989-09-13 CN claimed
EP-4288125-A1 COATED MEDICINAL PRODUCT AND METHOD FOR COATING A MEDICINAL PRODUCT Phenox GmbH (DE) 2023-12-13 EP disclosed
US-20210149307-A1 UNDERLAYER FILM-FORMING COMPOSITION, PATTERN-FORMING METHOD, AND COPOLYMER FOR FORMING UNDERLAYER FILM USED FOR PATTERN FORMATION Oji Holdings Corporation (JP) 2021-05-20 US disclosed
EP-3654102-A1 UNDERLAYER FILM-FORMING COMPOSITION, PATTERN-FORMING METHOD, AND COPOLYMER FOR FORMING UNDERLAYER FILM USED FOR PATTERN FORMATION Oji Holdings Corporation (JP) 2020-05-20 EP disclosed
CN-103119050-B Substituted saccharide compound and dental composition 3M创新有限公司 2016-08-24 CN disclosed
CN-101300036-A Coatings and articles including natural biodegradable polysaccharides SURMODICS INC (US) 2008-11-05 CN disclosed
CN-1033840-C Ultrasonic contrast medium and application for diagnosis treatment SCHERING AG (DE) 1997-01-22 CN disclosed
CN-1035437-A Ultrasonic contrast agents and manufacture method thereof and the application in diagnoses and treatment SCHERING AG (DE) 1989-09-13 CN disclosed