SCHEMBL7156502

SCHEMBL7156502

O=[N+]([O-])c1ccc(Oc2ccnc3c2ccc2c(Oc4ccc([N+](=O)[O-])c(OCc5ccccc5)c4)ccnc23)cc1OCc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.48
KMT2A Q03164 4/20 0.48
NPC1 O15118 2/20 0.48
RAB9A P51151 1/20 0.48
ATM Q13315 1/20 0.48
CYP11B1 P15538 4/20 0.46
CYP11B2 P19099 4/20 0.46
POLB P06746 1/20 0.42
CYP19A1 P11511 2/20 0.42
CTSV O60911 3/20 0.41
CTSL P07711 3/20 0.41
PIN1 Q13526 2/20 0.40
MYC P01106 1/20 0.39
MAX P61244 1/20 0.39
CTSB P07858 1/20 0.39
MAPT P10636 1/20 0.39
BACE1 P56817 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7152813 0.94 MEN1 (0.43) MEN1KMT2ANPC1RAB9AATM
SCHEMBL7154482 0.90 KMT2A (0.42) MEN1KMT2ANPC1RAB9AATM
SCHEMBL7552860 0.84 MEN1 (0.53) MEN1KMT2ANPC1RAB9AATM
SCHEMBL646471 0.82 MEN1 (0.54) MEN1KMT2ANPC1RAB9AATM
SCHEMBL30061165 0.82 MEN1 (0.54) MEN1KMT2ANPC1RAB9AATM
SCHEMBL27581338 0.82 MEN1 (0.51) MEN1KMT2ANPC1RAB9AATM
SCHEMBL5462629 0.81 MEN1 (0.46) MEN1KMT2ANPC1RAB9AATM
SCHEMBL7907625 0.80 MEN1 (0.54) MEN1KMT2ANPC1RAB9AATM
SCHEMBL12734031 0.78 MEN1 (0.50) MEN1KMT2ANPC1RAB9AATM
SCHEMBL5344847 0.78 MEN1 (0.50) MEN1KMT2ANPC1RAB9AATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6531632-B2 Reacting dihydroxy compound with halogenated o-nitrophenol INFINEON TECHNOLOGIES AG (DE) 2003-03-11 US disclosed
US-20020010370-A1 Bis-o-aminophenols and o-aminophenolcarboxylic acids and process for preparing the same POLARIS INNOVATIONS LIMITED (IE) 2002-01-24 US disclosed
EP-1132374-A2 Bis-o-aminophenols and o-aminophenolcarboxylic acids Infineon Technologies AG (DE) 2001-09-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020010370-A1 Bis-o-aminophenols and o-aminophenolcarboxylic acids and process for preparing the same FOS, POF1B, FOSB MEN1 3903/4885KMT2A 1691/4885NPC1 4202/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.