Known targets — ChEMBL curated mechanism
ABL1BMXBRAFBTKCHRNA4CHRNB2CSNK1EEGFRERBB2F10FLT1FLT3FLT4IGF1RINSRITKJAK3KDRKITOPRM1PARP1PARP2PDGFRBPIK3CDRAF1RETSLC18A2TECTXKdacAdacBdacCftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 4/20 | 0.43 |
| ▸ | CA1 | P00915 | 4/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.42 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.42 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.42 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL717091 | 1.00 | LMNA (0.50) | LMNAMAPTLARS1CA5ACTSK | |
| SCHEMBL7354344 | 1.00 | LMNA (0.50) | LMNAMAPTLARS1CA5ACTSK | |
| SCHEMBL21214961 | 0.89 | CA1 (0.47) | LMNALARS1CA5ACA1CA2 | |
| SCHEMBL29787834 | 0.88 | LMNA (0.56) | LMNAMAPTCA1CA2CYP2D6 | |
| SCHEMBL5396953 | 0.88 | LMNA (0.56) | LMNAMAPTCA1CA2CYP2D6 | |
| SCHEMBL5396950 | 0.88 | LMNA (0.56) | LMNAMAPTCA1CA2CYP2D6 | |
| SCHEMBL5221398 | 0.88 | LMNA (0.52) | LMNAMAPTCA1CA2CYP2D6 | |
| SCHEMBL4511022 | 0.88 | LMNA (0.52) | LMNAMAPTCA1CA2CYP2D6 | |
| SCHEMBL9443648 | 0.88 | LMNA (0.52) | LMNAMAPTCA1CA2CYP2D6 | |
| SCHEMBL718199 | 0.88 | LMNA (0.52) | LMNAMAPTCA1CA2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120192379-A | Marine cyclic peptide and synthesis method and application thereof | 内蒙古大学 | 2025-06-24 | — | — | CN | claimed |
| CN-120192379-A | Marine cyclic peptide and synthesis method and application thereof | 内蒙古大学 | 2025-06-24 | — | — | CN | disclosed |
| CN-116829949-A | Compositions for detecting or measuring analytes | 伯蒂斯有限公司 | 2023-09-29 | — | — | CN | disclosed |
| US-20220283131-A1 | COMPOSITION FOR DETECTING OR MEASURING ANALYTES | BERTIS CO., LTD. (KR) | 2022-09-08 | — | — | US | disclosed |
| CN-111153958-A | A modulator for enhancing immune function and its application method | 许洋 | 2020-05-15 | — | — | CN | disclosed |
| US-8724296-B2 | Solid electrolytic capacitor and fabrication method thereof | SANYO ELECTRIC CO., LTD. (JP) | 2014-05-13 | — | — | US | disclosed |
| US-8425805-B2 | Conductive polymer film, electronic device, and methods of producing the film and the device | SANYO ELECTRIC CO., LTD. (JP) | 2013-04-23 | — | — | US | disclosed |
| US-20120049136-A1 | CONDUCTIVE POLYMER FILM, ELECTRIC DEVICES AND METHODS FOR MANUFACTURING THE CONDUCTIVE POLYMER FILM | SANYO ELECTRIC CO., LTD. (JP) | 2012-03-01 | — | — | US | disclosed |
| US-20110051319-A1 | CONDUCTING POLYMER MEMBRANE, METHOD OF MANUFACTURING CONDUCTING POLYMER MEMBRANE, AND ELECTRONIC DEVICE | SANYO ELECTRIC CO., LTD. (JP) | 2011-03-03 | — | — | US | disclosed |
| US-20100271757-A1 | SOLID ELECTROLYTIC CAPACITOR AND FABRICATION METHOD THEREOF | SANYO ELECTRIC CO., LTD. (JP) | 2010-10-28 | — | — | US | disclosed |
| US-6946481-B1 | Endothelin antagonists | ABBOTT LABORATORIES (US) | 2005-09-20 | — | — | US | disclosed |
| EP-1501830-A1 | 7-ARYL-3,9-DIAZABICYCLO[3.3.1]NON-6-ENE DERIVATIVES AND THEIR USE AS RENIN INHIBITORS IN THE TREATMENT OF HYPERTENSION, CARDIOVASCULAR OR RENAL DISEASES | Actelion Pharmaceuticals Ltd. (CH) | 2005-02-02 | — | — | EP | disclosed |
| WO-2003093267-A1 | 7-ARYL-3,9-DIAZABICYCLO(3.3.1)NON-6-ENE DERIVATIVES AND THEIR USE AS RENIN INHIBITORS IN THE TREATMENT OF HYPERTENSION, CARDIOVASCULAR OR RENAL DISEASES | ACTELION PHARMACEUTICALS LTD (CH) | 2003-11-13 | — | — | WO | disclosed |
| WO-2002017912-A1 | ENDOTHELIN ANTAGONISTS | ABBOTT LABORATORIES (US) | 2002-03-07 | — | — | WO | disclosed |
| US-6162927-A | Endothelin antagonists | ABBOTT LABORATORIES (US) | 2000-12-19 | — | — | US | disclosed |
| EP-1003740-A2 | PYRROLIDINE-3-CARBOXYLIC ACID DERIVATIVES AND THEIR USE AS ENDOTHELIN ANTAGOISTS | Abbott Laboratories (US) | 2000-05-31 | — | — | EP | disclosed |
| WO-1999006397-A2 | PYRROLIDINE-3-CARBOXYLIC ACID DERIVATIVES AND THEIR USE AS ENDOTHELIN ANTAGONISTS | ABBOTT LABORATORIES (US) | 1999-02-11 | — | — | WO | disclosed |
| EP-0885215-A1 | NOVEL BENZO-1,3-DIOXOLYL- AND BENZOFURANYL SUBSTITUTED PYRROLIDINE DERIVATIVES AS ENDOTHELIN ANTAGONISTS | Abbott Laboratories (US) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997030045-A1 | NOVEL BENZO-1,3-DIOXOLYL- AND BENZOFURANYL SUBSTITUTED PYRROLIDINE DERIVATIVES AS ENDOTHELIN ANTAGONISTS | ABBOTT LABORATORIES (US) | 1997-08-21 | — | — | WO | disclosed |
| US-5110799-A | Inhibition of viral ribonucleotide reductase | MERCK & CO., INC. (US) | 1992-05-05 | — | — | US | disclosed |