Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 5/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | CCR6 | P51684 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13786 | 0.77 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2POLBDPP4LMNA | |
| SCHEMBL569156 | 0.77 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2POLBDPP4LMNA | |
| SCHEMBL88005 | 0.74 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2POLBDPP4LMNA | |
| SCHEMBL3258454 | 0.74 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2POLBDPP4LMNA | |
| SCHEMBL88004 | 0.74 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2POLBDPP4LMNA | |
| N,N-Diallyl-2-Bromoacetamide SCHEMBL5571993 | 0.74 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2POLBDPP4LMNA | |
| SCHEMBL49389 | 0.72 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2POLBDPP4LMNA | |
| SCHEMBL173228 | 0.72 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2POLBDPP4LMNA | |
| SCHEMBL8845450 | 0.72 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2POLBDPP4LMNA | |
| SCHEMBL692534 | 0.72 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2POLBDPP4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1232163-B1 | PRODUCTION OF DISUBSTITUTED PENTAFULVENS VIA LITHIATED SILYL-(HALO)ARENE INTERMEDIATES | ALBEMARLE CORP (US) | 2003-05-02 | — | — | EP | disclosed |
| EP-1232163-A1 | PRODUCTION OF DISUBSTITUTED PENTAFULVENS VIA LITHIATED SILYL-(HALO)ARENE INTERMEDIATES | ALBEMARLE CORPORATION (US) | 2002-08-21 | — | — | EP | disclosed |
| WO-2001038333-A1 | PRODUCTION OF DISUBSTITUTED PENTAFULVENS VIA LITHIATED SILYL-(HALO)ARENE INTERMEDIATES | ALBEMARLE CORPORATION (US) | 2001-05-31 | — | — | WO | disclosed |
| US-6084117-A | Production of silated haloarenes by selective silylation of polyhaloarenes | ALBEMARLE CORPORATION (US) | 2000-07-04 | — | — | US | disclosed |