SCHEMBL13786

SCHEMBL13786

C=CCN(CC=C)C(=O)N(CC=C)CC=C

nearest known ligand 0.56

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.56
SMN1; SMN2 Q16637 3/20 0.41
POLB P06746 1/20 0.37
LMNA P02545 4/20 0.37
DPP4 P27487 1/20 0.36
MAPT P10636 1/20 0.34
HPGD P15428 2/20 0.33
CYP1A2 P05177 1/20 0.33
ALOX12 P18054 1/20 0.33
CCR6 P51684 1/20 0.33
NPSR1 Q6W5P4 1/20 0.32
KDM4E B2RXH2 1/20 0.32
HTT P42858 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11665029 0.84 ALDH1A1 (0.48) ALDH1A1SMN1; SMN2POLBLMNADPP4
SCHEMBL29140220 0.84 ALDH1A1 (0.48) ALDH1A1SMN1; SMN2POLBLMNADPP4
SCHEMBL569156 0.81 ALDH1A1 (0.56) ALDH1A1SMN1; SMN2POLBLMNADPP4
SCHEMBL17841720 0.80 ALDH1A1 (0.45) ALDH1A1SMN1; SMN2POLBDPP4TSHR
SCHEMBL6922595 0.80 ALDH1A1 (0.45) ALDH1A1SMN1; SMN2POLBDPP4
SCHEMBL3258454 0.79 ALDH1A1 (0.54) ALDH1A1SMN1; SMN2POLBLMNADPP4
SCHEMBL88005 0.79 ALDH1A1 (0.54) ALDH1A1SMN1; SMN2POLBLMNADPP4
SCHEMBL88004 0.79 ALDH1A1 (0.54) ALDH1A1SMN1; SMN2POLBLMNADPP4
SCHEMBL8845450 0.77 ALDH1A1 (0.52) ALDH1A1SMN1; SMN2POLBLMNADPP4
SCHEMBL692534 0.77 ALDH1A1 (0.52) ALDH1A1SMN1; SMN2POLBLMNADPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220135914-A1 CLEANING AGENT COMPOSITION AND CLEANING METHOD NISSAN CHEMICAL CORPORATION (JP) 2022-05-05 US claimed
US-20130260649-A1 MULTI-PURPOSE, NON-CORROSIVE CLEANING COMPOSITIONS AND METHODS OF USE VITECH INTERNATIONAL, INC. 2013-10-03 US claimed
CN-101501084-A Polymeric viscosity modifiers PROCTER & GAMBLE (US) 2009-08-05 CN claimed
US-20090176689-A1 Tetrafluoroborate compounds, compositions and related methods of use VITECH INTERNATIONAL, INC. 2009-07-09 US claimed
EP-2046847-A2 POLYMERIC VISCOSITY MODIFIERS The Procter and Gamble Company (US) 2009-04-15 EP claimed
US-20080227772-A1 Diazabicyclic Aryl Derivatives as Nicotinic Acetylcholine Receptor Ligands NEUROSEARCH A/S 2008-09-18 US claimed
EP-1969115-A2 MULTIPURPOSE, NON-CORROSIVE CLEANING COMPOSITIONS AND METHODS OF USE Vitech International Inc. (US) 2008-09-17 EP claimed
US-20080033129-A1 Polymeric viscosity modifiers THE PROCTER & GAMBLE COMPANY 2008-02-07 US claimed
WO-2008015653-A2 POLYMERIC VISCOSITY MODIFIERS THE PROCTER & GAMBLE COMPANY (US) 2008-02-07 WO claimed
WO-2007128015-A2 METHOD FOR PRODUCING AT LEAST ONE CONDUCTIVE ELEMENT OF A PRINTED-CIRCUIT BOARD, PRINTED-CIRCUIT BOARD AND USE OF THIS METHOD AT & S AUSTRIA TECHNOLOGIE & SYSTEMTECHNIK AKTIENGESELLSCHAFT (AT) 2007-11-15 WO claimed
US-20070203049-A1 Multipurpose, non-corrosive cleaning compositions and methods of use WIN CHEMICALS LTD. (CA) 2007-08-30 US claimed
WO-2007096711-A2 MULTIPURPOSE, NON-CORROSIVE CLEANING COMPOSITIONS AND METHODS OF USE VITECH INTERNATIONAL, INC. (US) 2007-08-30 WO claimed
EP-0572792-B1 Tire tread composition BRIDGESTONE CORP (JP) 1998-12-09 EP claimed
EP-0572792-A1 Tire tread composition BRIDGESTONE CORPORATION (JP) 1993-12-08 EP claimed
US-5248722-A Functionalized elastomer, oxidized carbon black, reduced hysteresis BRIDGESTONE CORPORATION (JP) 1993-09-28 US claimed
EP-0296483-B1 PREPARATION OF ASCORBIC ACID 6-ESTERS F. HOFFMANN-LA ROCHE AG (CH) 1992-05-06 EP claimed
US-4038371-A DISMUTATION OF TRICHLOROSILANE RHONE-POULENC INDUSTRIES (FR) 1977-07-26 US claimed
JP-10235173-A None JP disclosed
US-4075225-A Pyrrolo[2,1-b][3]benzazepines MERCK & CO., INC. (US) 1978-02-21 US disclosed
US-4038371-A DISMUTATION OF TRICHLOROSILANE RHONE-POULENC INDUSTRIES (FR) 1977-07-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080227772-A1 Diazabicyclic Aryl Derivatives as Nicotinic Acetylcholine Receptor Ligands CHRNA6, CHRNA10, CHRNA2 ALDH1A1 1094/4885SMN1; SMN2 364/4885POLB 3892/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.