Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 11/20 | 0.72 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.65 |
| ▸ | AR | P10275 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | USP2 | O75604 | 1/20 | 0.65 |
| ▸ | ESR1 | P03372 | 1/20 | 0.65 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.65 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.65 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.65 |
| ▸ | TST | Q16762 | 1/20 | 0.65 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.59 |
| ▸ | PGR | P06401 | 3/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9050757 | 1.00 | VDR (0.72) | VDRADRA1ALMNAABCB11AR | |
| SCHEMBL7156998 | 0.92 | VDR (0.62) | VDRADRA1ALMNAABCB11AR | |
| SCHEMBL14489178 | 0.92 | VDR (0.62) | VDRADRA1ALMNAABCB11AR | |
| SCHEMBL15081679 | 0.92 | VDR (0.62) | VDRADRA1ALMNAABCB11AR | |
| SCHEMBL12849126 | 0.90 | VDR (0.57) | VDRADRA1AABCB11NR1I2PGR | |
| SCHEMBL9051796 | 0.89 | VDR (0.64) | VDRADRA1ALMNAABCB11AR | |
| SCHEMBL15083872 | 0.89 | VDR (0.59) | VDRADRA1ALMNAABCB11AR | |
| SCHEMBL7153800 | 0.88 | VDR (0.72) | VDRADRA1ALMNAABCB11AR | |
| SCHEMBL9980582 | 0.88 | VDR (0.72) | VDRADRA1ALMNAABCB11AR | |
| SCHEMBL7151839 | 0.85 | VDR (0.58) | VDRADRA1ALMNAABCB11AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0506388-B1 | 1-Hydroxyvitamin D derivatives | NISSHIN FLOUR MILLING CO (JP) | 1996-06-05 | — | — | EP | disclosed |
| EP-0506388-A1 | 1-Hydroxyvitamin D derivatives | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1992-09-30 | — | — | EP | disclosed |