Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9271255 | 0.77 | GABRA1 (0.52) | GABRA1GABRG2GABRB3TSHRGABRB2 | |
| Hydrochloric Acid SCHEMBL30662632 | 0.76 | GABRA1 (0.46) | GABRA1GABRG2GABRB3TSHRGABRB2 | |
| SCHEMBL5548772 | 0.75 | GABRA1 (0.50) | GABRA1GABRG2GABRB3TSHRGABRB2 | |
| SCHEMBL9988540 | 0.75 | GABRA1 (0.50) | GABRA1GABRG2GABRB3TSHRGABRB2 | |
| Hydrochloric Acid SCHEMBL4232392 | 0.74 | GABRA1 (0.44) | GABRA1GABRG2GABRB3TSHRGABRB2 | |
| Hydrochloric Acid SCHEMBL9581720 | 0.74 | GABRA1 (0.44) | GABRA1GABRG2GABRB3TSHRGABRB2 | |
| Hydrochloric Acid SCHEMBL27493440 | 0.74 | NISCH (0.44) | GABRA1GABRG2GABRB3TSHRGABRB2 | |
| Hydrochloric Acid SCHEMBL9565693 | 0.74 | GABRA1 (0.44) | GABRA1GABRG2GABRB3TSHRGABRB2 | |
| SCHEMBL2048068 | 0.73 | GABRA1 (0.60) | GABRA1GABRG2GABRB3TSHRGABRB2 | |
| SCHEMBL22026422 | 0.73 | GABRA1 (0.48) | GABRA1GABRG2GABRB3TSHRGABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108884282-B | Polyethylene and molded article thereof | 日本聚乙烯株式会社 | 2021-06-08 | — | — | CN | disclosed |
| CN-107428863-B | Polyethylene for pipe and joint, and molded body thereof | 日本聚乙烯株式会社 | 2020-03-06 | — | — | CN | disclosed |
| US-20030054952-A1 | Component of catalyst for polymerizing olefin, catalyst for polymerizing olefin and process for polymerizing olefin | JAPAN POLYCHEM CORPORATION (JP) | 2003-03-20 | — | — | US | disclosed |
| US-6531552-B2 | Coordination catalyst on silicate support | JAPAN POLYCHEM CORPORATION (JP) | 2003-03-11 | — | — | US | disclosed |
| US-20020004447-A1 | Olefin polymerization catalyst and method for polymerizing olefin using the same | JAPAN POLYCHEM CORPORATION (JP) | 2002-01-10 | — | — | US | disclosed |