Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAGLA | Q9Y4D2 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL715715 | 1.00 | DAGLA (0.33) | DAGLA | |
| SCHEMBL715717 | 0.87 | DAGLA (0.36) | DAGLA | |
| SCHEMBL715718 | 0.87 | DAGLA (0.36) | DAGLA | |
| SCHEMBL714844 | 0.82 | DAGLA (0.34) | DAGLA | |
| SCHEMBL714845 | 0.82 | DAGLA (0.34) | DAGLA | |
| SCHEMBL714843 | 0.82 | DAGLA (0.34) | DAGLA | |
| SCHEMBL7098281 | 0.75 | POLB (0.30) | — | |
| SCHEMBL7098280 | 0.75 | POLB (0.30) | — | |
| SCHEMBL10370898 | 0.71 | DAGLA (0.35) | DAGLA | |
| SCHEMBL10370899 | 0.71 | DAGLA (0.35) | DAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8124794-B2 | Method for the asymmetric synthesis of beta-lactone compounds | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) | 2012-02-28 | — | — | US | disclosed |
| US-7799826-B2 | Inhibition of fatty acid synthase by beta-lactones and other compounds for inhibition of cellular proliferation | BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2010-09-21 | — | — | US | disclosed |
| US-20100173982-A1 | NOVEL METHOD FOR THE ASYMMETRIC SYNTHESIS OF BETA-LACTONE COMPOUNDS | THE BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2010-07-08 | — | — | US | disclosed |
| US-7728153-B2 | Method for the asymmetric synthesis of beta-lactone compounds | THE BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2010-06-01 | — | — | US | disclosed |
| US-20060258620-A1 | Novel method for the asymmetric synthesis of beta-lactone compounds | BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2006-11-16 | — | — | US | disclosed |
| US-20040024050-A1 | Inhibition of fatty acid synthase by beta-lactones and other compounds for inhibition of cellular proliferation | BURNHAM INSTITUTE FOR MEDICAL RESEARCH | 2004-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100173982-A1 | NOVEL METHOD FOR THE ASYMMETRIC SYNTHESIS OF BETA-LACTONE COMPOUNDS | FASN, COASY, FADS1 | DAGLA 228/4885 |
| US-20060258620-A1 | Novel method for the asymmetric synthesis of beta-lactone compounds | FASN, COASY, FADS1 | DAGLA 228/4885 |
| US-20040024050-A1 | Inhibition of fatty acid synthase by beta-lactones and other compounds for inhibition of cellular proliferation | FASN, FADS1, FADS2 | DAGLA 275/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.