SCHEMBL7098281

SCHEMBL7098281

C=C[C@H]1C(=O)O[C@H]1C(C(=O)OC(c1ccccc1)c1ccccc1)=C(C)C=C(C)CC(C)CCCC

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7098280 1.00 POLB (0.30) POLB
SCHEMBL7099012 0.87 DAGLA (0.33) POLB
SCHEMBL7099016 0.87 DAGLA (0.33) POLB
SCHEMBL715716 0.75 DAGLA (0.33)
SCHEMBL715715 0.75 DAGLA (0.33)
SCHEMBL7094495 0.71 PRKCA (0.32)
SCHEMBL7094498 0.71 PRKCA (0.32)
SCHEMBL7094794 0.71 CNR1 (0.30)
SCHEMBL7094793 0.71 CNR1 (0.30)
SCHEMBL3313686 0.70 PRKCA (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003088975-A1 INHIBITION OF FATTY ACID SYNTHASE BY BETA-LACTONES AND OTHER COMPOUNDS FOR INHIBITION OF CELLULAR PROLIFERATION THE BURNHAM INSTITUTE (US) 2003-10-30 WO disclosed