Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | ALDH2 | P05091 | 4/20 | 0.59 |
| ▸ | MGLL | Q99685 | 4/20 | 0.52 |
| ▸ | PHGDH | O43175 | 3/20 | 0.52 |
| ▸ | PKM | P14618 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 5/20 | 0.41 |
| ▸ | CA1 | P00915 | 5/20 | 0.41 |
| ▸ | CA9 | Q16790 | 5/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL283658 | 0.92 | ALDH1A1 (0.68) | ALDH1A1ALDH2MGLLPHGDHPKM | |
| SCHEMBL3480745 | 0.91 | ALDH1A1 (0.57) | ALDH1A1ALDH2MGLLPHGDHPKM | |
| SCHEMBL10798862 | 0.86 | ALDH1A1 (0.61) | ALDH1A1ALDH2MGLLPHGDHPKM | |
| SCHEMBL9605348 | 0.86 | ALDH1A1 (0.59) | ALDH1A1ALDH2MGLLPHGDHPKM | |
| SCHEMBL284585 | 0.84 | MGLL (0.60) | ALDH1A1ALDH2MGLLPHGDHPKM | |
| SCHEMBL10798275 | 0.84 | MGLL (0.60) | ALDH1A1ALDH2MGLLPHGDHPKM | |
| SCHEMBL10803554 | 0.84 | MGLL (0.60) | ALDH1A1ALDH2MGLLPHGDHPKM | |
| SCHEMBL440818 | 0.84 | MGLL (0.60) | ALDH1A1ALDH2MGLLPHGDHPKM | |
| SCHEMBL10803225 | 0.84 | MGLL (0.60) | ALDH1A1ALDH2MGLLPHGDHPKM | |
| SCHEMBL10798664 | 0.84 | MGLL (0.60) | ALDH1A1ALDH2MGLLPHGDHPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6531428-B2 | Wear inhibiting and corrosion inhibiting effective amount of a zinc dialkyldithiophosphate and a thiobis-, dithiobis-, or alkylenebis-dithiocarbamate | CHEVRON ORONITE COMPANY LLC | 2003-03-11 | — | — | US | disclosed |
| US-20020098990-A1 | LOW PHOSPHOROUS ENGINE OIL COMPOSITION AND ADDITIVE COMPOSITIONS | NAKAZATO MORIKUNI (JP) | 2002-07-25 | — | — | US | disclosed |