Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.59 |
| ▸ | MAOB | P27338 | 2/20 | 0.59 |
| ▸ | F10 | P00742 | 17/20 | 0.52 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | CALML3 | P27482 | 1/20 | 0.48 |
| ▸ | SDHA | P31040 | 1/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7157295 | 1.00 | MAOA (0.59) | MAOAMAOBF10F2LMNA | |
| SCHEMBL7161503 | 0.96 | MAOA (0.55) | MAOAMAOBF10F2LMNA | |
| SCHEMBL7161497 | 0.96 | MAOA (0.55) | MAOAMAOBF10F2LMNA | |
| SCHEMBL7156712 | 0.89 | MAOA (0.64) | MAOAMAOBF10F2LMNA | |
| SCHEMBL7156723 | 0.89 | MAOA (0.64) | MAOAMAOBF10F2LMNA | |
| SCHEMBL7161224 | 0.87 | MAOB (0.79) | MAOAMAOBF10LMNAPTGS1 | |
| SCHEMBL7157274 | 0.87 | MAOA (0.53) | MAOAMAOBF10F2ITGB3 | |
| SCHEMBL7157275 | 0.87 | MAOA (0.53) | MAOAMAOBF10F2ITGB3 | |
| SCHEMBL7161225 | 0.87 | MAOB (0.79) | MAOAMAOBF10LMNAPTGS1 | |
| SCHEMBL7955642 | 0.87 | MAOB (0.56) | MAOAMAOBF10F2ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6255304-B1 | AIDS THERAPY | PHARMACIA & UPJOHN COMPANY | 2001-07-03 | — | — | US | claimed |
| US-6537986-B2 | With thiourea, thioamide, or dithiocarbamate functionality; (S)-N-(((3-(3-fluoro-4-morpholinyl)phenyl)-2-oxo-5 -oxazolidinyl)methyl)thioacetamide for example; treats multiple-resistant staphylococci | PHARMACIA & UPJOHN COMPANY | 2003-03-25 | — | — | US | disclosed |