Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 4/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2207927 | 1.00 | THRB (0.71) | THRBLMNAALDH1A1TDP1L3MBTL1 | |
| SCHEMBL10581335 | 1.00 | THRB (0.71) | THRBLMNAALDH1A1TDP1L3MBTL1 | |
| SCHEMBL9742446 | 1.00 | THRB (0.71) | THRBLMNAALDH1A1TDP1L3MBTL1 | |
| SCHEMBL1954558 | 0.96 | THRB (0.67) | THRBLMNAALDH1A1TDP1L3MBTL1 | |
| SCHEMBL4523446 | 0.89 | — | — | |
| SCHEMBL4602198 | 0.86 | THRB (0.87) | THRBLMNAALDH1A1TDP1L3MBTL1 | |
| SCHEMBL25959822 | 0.86 | — | — | |
| SCHEMBL1164867 | 0.84 | THRB (0.62) | THRBLMNAALDH1A1TDP1L3MBTL1 | |
| SCHEMBL100643 | 0.84 | THRB (0.62) | THRBLMNAALDH1A1TDP1L3MBTL1 | |
| SCHEMBL705919 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6632953-B1 | Metal complex comprising a phospholane as claimed in any of claim 1 and a central atom selected from the group of Rh, Ru, Ir, Pd, Pt, Ni. asymmetric hydrogenation of compounds by reacting the starting compounds to be hydrogenated with | BASF AKTIENGESELLSCHAFT (DE) | 2003-10-14 | — | — | US | disclosed |
| EP-0992481-B1 | Process for the asymmetric hydrogenation of beta-ketoesters | BASF AG (DE) | 2003-05-21 | — | — | EP | disclosed |
| EP-1082328-B1 | PRODUCTION OF OPTICALLY ACTIVE PHOSPHOLANES | BASF AG (DE) | 2002-11-20 | — | — | EP | disclosed |
| US-6359165-B1 | CATALYTIC HYDROGENATION OF CORRESPONDING KETOESTER USING RUTHENIUM COMPLEX | BASF AKTIENEGESELLSCHAFT (DE) | 2002-03-19 | — | — | US | disclosed |
| EP-1082328-A1 | PRODUCTION OF OPTICALLY ACTIVE PHOSPHOLANES | BASF AKTIENGESELLSCHAFT (DE) | 2001-03-14 | — | — | EP | disclosed |
| EP-0992481-A1 | Process for the asymmetric hydrogenation of beta-ketoesters | BASF AKTIENGESELLSCHAFT (DE) | 2000-04-12 | — | — | EP | disclosed |
| WO-1999062917-A1 | PRODUCTION OF OPTICALLY ACTIVE PHOSPHOLANES | BASF AKTIENGESELLSCHAFT (DE) | 1999-12-09 | — | — | WO | disclosed |
| US-4820880-A | HYDROGENOLYSIS OF HEXITOLS USING COPPER CHROMITE | MICHIGAN BIOTECHNOLOGY INSTITUTE (US) | 1989-04-11 | — | — | US | disclosed |