Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G1B | P04054 | 2/20 | 0.47 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6871225 | 0.82 | LMNA (0.41) | PLA2G1BATG4BL3MBTL1CA12CA1 | |
| SCHEMBL2441746 | 0.79 | PLA2G1B (0.45) | PLA2G1BATG4BL3MBTL1LMNACHRM2 | |
| SCHEMBL336981 | 0.79 | CA2 (0.47) | CA12CA1CA2KDM4EALDH1A1 | |
| SCHEMBL6877846 | 0.78 | TAAR1 (0.52) | PLA2G1BATG4BTAAR1LMNAKDM4E | |
| SCHEMBL6077314 | 0.78 | LMNA (0.53) | PLA2G1BATG4BL3MBTL1TAAR1LMNA | |
| SCHEMBL6076744 | 0.73 | HPGD (0.47) | PLA2G1BATG4BL3MBTL1LMNACHRM2 | |
| SCHEMBL3971719 | 0.72 | LMNA (0.52) | PLA2G1BATG4BL3MBTL1TAAR1CA12 | |
| SCHEMBL17070611 | 0.70 | TAAR1 (0.50) | L3MBTL1TAAR1MAOB | |
| SCHEMBL4579423 | 0.70 | TAAR1 (0.50) | L3MBTL1TAAR1MAOB | |
| SCHEMBL15079869 | 0.70 | MAOB (0.58) | L3MBTL1TAAR1LTA4HMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004103278-A2 | ACYL SULFONAMIDES AS INHIBITORS OF HIV INTEGRASE | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-12-02 | — | — | WO | disclosed |