Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | DRD4 | P21917 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10983422 | 0.85 | ATM (0.74) | TDP1MAPTALDH1A1HTTDRD4 | |
| SCHEMBL8541852 | 0.84 | MAPT (0.61) | MAPTALDH1A1L3MBTL1KDM4EGLA | |
| SCHEMBL8482810 | 0.83 | L3MBTL1 (0.78) | MAPTALDH1A1HTTDRD4L3MBTL1 | |
| SCHEMBL11743418 | 0.83 | ATM (0.66) | TDP1MAPTALDH1A1HTTDRD4 | |
| SCHEMBL8541877 | 0.83 | KDM4E (0.69) | MAPTDRD4L3MBTL1KDM4EGLA | |
| SCHEMBL7159605 | 0.83 | MAPT (0.60) | MAPTALDH1A1L3MBTL1KDM4EGLA | |
| SCHEMBL8539736 | 0.83 | KCNH2 (0.70) | MAPTALDH1A1DRD4LMNAL3MBTL1 | |
| SCHEMBL7882866 | 0.83 | MAPT (0.67) | MAPTALDH1A1L3MBTL1KDM4EGLA | |
| SCHEMBL11740885 | 0.82 | ATM (0.68) | TDP1MAPTALDH1A1HTTDRD4 | |
| SCHEMBL11740527 | 0.82 | ATM (0.68) | TDP1MAPTALDH1A1HTTDRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0768898-B1 | CASCADE-POLYMER COMPLEXES AND METHODS OF PRODUCING THE SAME | SCHERING AG (DE) | 2003-04-09 | — | — | EP | disclosed |
| US-6248306-B1 | MEDICAL DIAGNOSIS | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-06-19 | — | — | US | disclosed |
| EP-0485045-B1 | Mono-N-substituted 1,4,7,10-Tetraazacyclododecan-derivatives, process for their preparation and pharmaceutical agent containing them | SCHERING AG (DE) | 1998-12-30 | — | — | EP | disclosed |
| EP-0768898-A1 | CASCADE-POLYMER COMPLEXES AND METHODS OF PRODUCING THE SAME | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-04-23 | — | — | EP | disclosed |
| WO-1996001655-A1 | CASCADE-POLYMER COMPLEXES AND METHODS OF PRODUCING THE SAME | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-01-25 | — | — | WO | disclosed |
| US-5277895-A | Nuclear magnetic resonance | SCHERING AKTIENGESELLSCHAFT (DE) | 1994-01-11 | — | — | US | disclosed |
| EP-0485045-A2 | Mono-N-substituted 1,4,7,10-Tetraazacyclododecan-derivatives, process for their preparation and pharmaceutical agent containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-05-13 | — | — | EP | disclosed |