Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.68 |
| ▸ | CA1 | P00915 | 1/20 | 0.64 |
| ▸ | CA2 | P00918 | 1/20 | 0.64 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | CASP3 | P42574 | 1/20 | 0.55 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.55 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.55 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | DHODH | Q02127 | 1/20 | 0.53 |
| ▸ | ALPL | P05186 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16195442 | 0.90 | RXRA (0.60) | RXRACA1CA2NR4A2SMN1; SMN2 | |
| SCHEMBL2043183 | 0.86 | CA1 (0.87) | RXRACA1CA2NR4A2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6705880 | 0.84 | CA1 (0.83) | RXRACA1CA2NR4A2SMN1; SMN2 | |
| SCHEMBL29128751 | 0.84 | RXRA (0.72) | RXRACA1CA2NR4A2KDM4E | |
| SCHEMBL29572748 | 0.84 | RXRA (0.67) | RXRACA1CA2NR4A2KDM4E | |
| SCHEMBL3639698 | 0.84 | SMN1; SMN2 (0.74) | RXRACA1CA2SMN1; SMN2NPC1 | |
| SCHEMBL16488615 | 0.83 | DHODH (0.69) | RXRADHODHAURKATPX2 | |
| SCHEMBL15814719 | 0.83 | DHODH (0.69) | RXRADHODHAURKATPX2 | |
| SCHEMBL12774551 | 0.83 | CA1 (0.66) | RXRACA1CA2SMN1; SMN2NPC1 | |
| SCHEMBL3350034 | 0.83 | HPGD (0.55) | RXRACA1CA2NR4A2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6541185-B1 | Thin film of liquid crystal polymer and dichroism compound | JAPAN CHEMICAL INNOVATION INSTITUTE (JP) | 2003-04-01 | — | — | US | disclosed |